Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   RNU01_RS06275 Genome accession   NZ_CP134801
Coordinates   1196712..1197686 (+) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain SA73_2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1191712..1202686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RNU01_RS06240 rpmG 1192172..1192321 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  RNU01_RS06245 - 1192530..1193069 (+) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  RNU01_RS06250 - 1193081..1194544 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  RNU01_RS06255 - 1194525..1194728 (+) 204 WP_000087561.1 YqgQ family protein -
  RNU01_RS06260 - 1194725..1195711 (+) 987 WP_000161314.1 ROK family glucokinase -
  RNU01_RS06265 - 1195711..1196040 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  RNU01_RS06270 - 1196037..1196660 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  RNU01_RS06275 comGA 1196712..1197686 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  RNU01_RS06280 comGB 1197658..1198728 (+) 1071 WP_311904905.1 competence type IV pilus assembly protein ComGB Machinery gene
  RNU01_RS06285 comGC 1198742..1199053 (+) 312 WP_311904906.1 competence type IV pilus major pilin ComGC Machinery gene
  RNU01_RS06290 comGD 1199031..1199477 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  RNU01_RS06295 comGE 1199464..1199763 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  RNU01_RS06300 comGF 1199681..1200178 (+) 498 WP_029642894.1 competence type IV pilus minor pilin ComGF Machinery gene
  RNU01_RS06305 - 1200275..1200421 (+) 147 WP_001789879.1 hypothetical protein -
  RNU01_RS06310 - 1200411..1200935 (+) 525 WP_001015119.1 shikimate kinase -
  RNU01_RS06315 gcvT 1201094..1202185 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=883771 RNU01_RS06275 WP_000697220.1 1196712..1197686(+) (comGA) [Staphylococcus aureus strain SA73_2]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=883771 RNU01_RS06275 WP_000697220.1 1196712..1197686(+) (comGA) [Staphylococcus aureus strain SA73_2]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1