Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AABJ53_RS15255 Genome accession   NZ_AP027622
Coordinates   3057893..3058483 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain PSJ-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3052893..3063483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ53_RS15215 (VEE42_28760) yidF 3053015..3053512 (+) 498 WP_000148061.1 radical SAM protein -
  AABJ53_RS15220 (VEE42_28770) emrD 3053520..3054704 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  AABJ53_RS15225 ysdE 3054786..3054860 (+) 75 WP_211180519.1 protein YsdE -
  AABJ53_RS15230 tisB 3054984..3055068 (-) 85 Protein_2963 type I toxin-antitoxin system toxin TisB -
  AABJ53_RS15235 - 3055065..3055178 (-) 114 Protein_2964 hypothetical protein -
  AABJ53_RS15240 ivbL 3055632..3055730 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  AABJ53_RS15245 (VEE42_28780) ilvB 3055836..3057524 (+) 1689 WP_021570996.1 acetolactate synthase large subunit -
  AABJ53_RS15250 (VEE42_28790) ilvN 3057528..3057818 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  AABJ53_RS15255 (VEE42_28800) letA 3057893..3058483 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  AABJ53_RS15260 (VEE42_28810) uhpB 3058483..3059985 (+) 1503 WP_021570995.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  AABJ53_RS15265 (VEE42_28820) uhpC 3059995..3061314 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  AABJ53_RS15270 (VEE42_28830) uhpT 3061452..3062843 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=88083 AABJ53_RS15255 WP_000633668.1 3057893..3058483(+) (letA) [Escherichia coli strain PSJ-12]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=88083 AABJ53_RS15255 WP_000633668.1 3057893..3058483(+) (letA) [Escherichia coli strain PSJ-12]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCACTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment