Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   RJW49_RS07115 Genome accession   NZ_CP134477
Coordinates   1386000..1387349 (-) Length   449 a.a.
NCBI ID   WP_012027301.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1381000..1392349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS07095 (RJW49_07095) pbp2b 1381222..1383297 (-) 2076 WP_024393197.1 penicillin-binding protein PBP2B -
  RJW49_RS07100 (RJW49_07100) abc-f 1383374..1384675 (-) 1302 WP_074393324.1 ribosomal protection-like ABC-F family protein -
  RJW49_RS07105 (RJW49_07105) - 1384662..1384934 (-) 273 WP_014735627.1 hypothetical protein -
  RJW49_RS07110 (RJW49_07110) vicX 1385190..1385993 (-) 804 WP_012027300.1 MBL fold metallo-hydrolase Regulator
  RJW49_RS07115 (RJW49_07115) micB 1386000..1387349 (-) 1350 WP_012027301.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RJW49_RS07120 (RJW49_07120) micA 1387342..1388046 (-) 705 WP_004298854.1 response regulator YycF Regulator
  RJW49_RS07125 (RJW49_07125) - 1388240..1389001 (+) 762 WP_012027304.1 amino acid ABC transporter ATP-binding protein -
  RJW49_RS07130 (RJW49_07130) - 1389012..1389851 (+) 840 WP_012027305.1 transporter substrate-binding domain-containing protein -
  RJW49_RS07135 (RJW49_07135) - 1389866..1390564 (+) 699 WP_012028333.1 amino acid ABC transporter permease -
  RJW49_RS07140 (RJW49_07140) - 1390579..1391238 (+) 660 WP_014735626.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51079.14 Da        Isoelectric Point: 4.4857

>NTDB_id=880221 RJW49_RS07115 WP_012027301.1 1386000..1387349(-) (micB) [Streptococcus suis strain NLS40]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYWDNKQIKQLNQKVNALIEGNYADLLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=880221 RJW49_RS07115 WP_012027301.1 1386000..1387349(-) (micB) [Streptococcus suis strain NLS40]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATTGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCCGATCTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCCCTCAATGATTTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTGGCGCCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTATAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.725

97.105

0.677
  vicK Streptococcus mutans UA159

70.72

89.755

0.635