Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   RJW49_RS02115 Genome accession   NZ_CP134477
Coordinates   417468..418760 (+) Length   430 a.a.
NCBI ID   WP_074393504.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 412468..423760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS02090 (RJW49_02090) - 413273..413914 (+) 642 WP_014735510.1 response regulator transcription factor -
  RJW49_RS02095 (RJW49_02095) - 413964..415364 (+) 1401 WP_074393507.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RJW49_RS02100 (RJW49_02100) - 415366..415737 (+) 372 WP_074393506.1 S1 RNA-binding domain-containing protein -
  RJW49_RS02105 (RJW49_02105) cysK 415763..416689 (-) 927 WP_012774985.1 cysteine synthase A -
  RJW49_RS02110 (RJW49_02110) - 416779..417411 (-) 633 WP_014735512.1 YigZ family protein -
  RJW49_RS02115 (RJW49_02115) comFA/cflA 417468..418760 (+) 1293 WP_074393504.1 DEAD/DEAH box helicase Machinery gene
  RJW49_RS02120 (RJW49_02120) - 418753..419418 (+) 666 Protein_380 ComF family protein -
  RJW49_RS02125 (RJW49_02125) hpf 419495..420037 (+) 543 WP_014735514.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48974.61 Da        Isoelectric Point: 9.1823

>NTDB_id=880207 RJW49_RS02115 WP_074393504.1 417468..418760(+) (comFA/cflA) [Streptococcus suis strain NLS40]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKNF
PITKCLKWKGQLTDWQQRISDGLVANVENNRVTLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSCFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAVAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=880207 RJW49_RS02115 WP_074393504.1 417468..418760(+) (comFA/cflA) [Streptococcus suis strain NLS40]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTTTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAAATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGTGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCTGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTTCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGTGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGAGTCGGAAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAGTCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(294-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae Rx1

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae D39

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae R6

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae TIGR4

66.125

100

0.663
  comFA/cflA Streptococcus mitis SK321

65.429

100

0.656
  comFA Lactococcus lactis subsp. cremoris KW2

53.652

92.326

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

37.701

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363