Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AABJ98_RS14305 Genome accession   NZ_AP027599
Coordinates   2898436..2899026 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain LR-71-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2893436..2904026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ98_RS14290 (VEE28_27910) uhpT 2894076..2895467 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  AABJ98_RS14295 (VEE28_27920) uhpC 2895605..2896924 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  AABJ98_RS14300 (VEE28_27930) uhpB 2896934..2898436 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  AABJ98_RS14305 (VEE28_27940) letA 2898436..2899026 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  AABJ98_RS14310 (VEE28_27950) ilvN 2899102..2899392 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  AABJ98_RS14315 (VEE28_27960) ilvB 2899396..2901084 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  AABJ98_RS14320 ivbL 2901190..2901288 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  AABJ98_RS14325 tisB 2901853..2901942 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  AABJ98_RS14330 ysdE 2902066..2902140 (-) 75 WP_211180519.1 protein YsdE -
  AABJ98_RS14335 (VEE28_27980) emrD 2902222..2903406 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  AABJ98_RS14340 (VEE28_27990) yidF 2903414..2903911 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=87841 AABJ98_RS14305 WP_000633668.1 2898436..2899026(-) (letA) [Escherichia coli strain LR-71-1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=87841 AABJ98_RS14305 WP_000633668.1 2898436..2899026(-) (letA) [Escherichia coli strain LR-71-1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment