Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   RIM64_RS05385 Genome accession   NZ_CP133951
Coordinates   1104846..1105583 (-) Length   245 a.a.
NCBI ID   WP_115266912.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain JMC111     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1099846..1110583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM64_RS05370 (RIM64_05370) - 1101838..1102119 (-) 282 WP_080332480.1 lactococcin 972 family bacteriocin -
  RIM64_RS05375 (RIM64_05375) - 1102599..1103450 (-) 852 WP_165619621.1 co-chaperone YbbN -
  RIM64_RS05380 (RIM64_05380) - 1104243..1104473 (-) 231 WP_043038961.1 Blp family class II bacteriocin -
  RIM64_RS05385 (RIM64_05385) comE/blpR 1104846..1105583 (-) 738 WP_115266912.1 response regulator transcription factor Regulator
  RIM64_RS05390 (RIM64_05390) - 1106329..1106634 (-) 306 WP_012677981.1 AraC family ligand binding domain-containing protein -
  RIM64_RS05395 (RIM64_05395) - 1106636..1106974 (-) 339 WP_014622843.1 cupin domain-containing protein -
  RIM64_RS05400 (RIM64_05400) - 1107002..1107757 (-) 756 WP_043030786.1 class I SAM-dependent methyltransferase -
  RIM64_RS05405 (RIM64_05405) - 1108017..1108472 (+) 456 WP_043030785.1 DUF1836 domain-containing protein -
  RIM64_RS05410 (RIM64_05410) - 1108456..1109106 (+) 651 WP_043030784.1 hemolysin III family protein -
  RIM64_RS05415 (RIM64_05415) - 1109217..1110122 (+) 906 WP_115266913.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28956.44 Da        Isoelectric Point: 7.8609

>NTDB_id=877712 RIM64_RS05385 WP_115266912.1 1104846..1105583(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain JMC111]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=877712 RIM64_RS05385 WP_115266912.1 1104846..1105583(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain JMC111]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATATTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGTATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATCCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-240)

Response regulator receiver domain (Response_reg)

(18-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.545

98.776

0.539
  comE/comE1 Streptococcus equinus JB1

45.041

98.776

0.445
  comE/comE2 Streptococcus equinus JB1

37.295

99.592

0.371