Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   RIM64_RS02625 Genome accession   NZ_CP133951
Coordinates   515875..516624 (+) Length   249 a.a.
NCBI ID   WP_111690344.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain JMC111     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 510875..521624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM64_RS02595 (RIM64_02595) - 511170..511481 (+) 312 WP_256608820.1 recombinase family protein -
  RIM64_RS02600 (RIM64_02600) - 511497..511997 (+) 501 WP_228274005.1 DUF4368 domain-containing protein -
  RIM64_RS02605 (RIM64_02605) - 512118..513086 (+) 969 WP_165619552.1 helix-hairpin-helix domain-containing protein -
  RIM64_RS02610 (RIM64_02610) rlmD 513083..514450 (+) 1368 WP_165619551.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  RIM64_RS02615 (RIM64_02615) - 514771..515028 (+) 258 WP_038674051.1 Blp family class II bacteriocin -
  RIM64_RS02620 (RIM64_02620) - 515045..515248 (+) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  RIM64_RS02625 (RIM64_02625) comE/blpR 515875..516624 (+) 750 WP_111690344.1 LytTR family DNA-binding domain-containing protein Regulator
  RIM64_RS10480 - 516624..517958 (+) 1335 WP_115266688.1 sensor histidine kinase -
  RIM64_RS02635 (RIM64_02635) - 518076..518210 (-) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  RIM64_RS02640 (RIM64_02640) - 518310..519668 (-) 1359 WP_115266689.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29217.65 Da        Isoelectric Point: 8.4602

>NTDB_id=877700 RIM64_RS02625 WP_111690344.1 515875..516624(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain JMC111]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRSHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=877700 RIM64_RS02625 WP_111690344.1 515875..516624(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain JMC111]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGTCTCACCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTTTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

40.586

95.984

0.39
  comE/comE2 Streptococcus equinus JB1

36.29

99.598

0.361