Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AABJ83_RS22035 Genome accession   NZ_AP027563
Coordinates   4501046..4501678 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain LR-58-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4496046..4506678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ83_RS22010 (VEE04_41890) yheS 4496215..4498128 (+) 1914 WP_000634840.1 ABC transporter ATP-binding protein -
  AABJ83_RS22015 (VEE04_41900) yheT 4498128..4499150 (+) 1023 WP_000057395.1 hydrolase -
  AABJ83_RS22020 (VEE04_41910) yheU 4499144..4499362 (+) 219 WP_000907085.1 YheU family protein -
  AABJ83_RS22025 (VEE04_41920) prkB 4499416..4500285 (+) 870 WP_001274680.1 phosphoribulokinase -
  AABJ83_RS22030 (VEE04_41930) yhfA 4500340..4500744 (-) 405 WP_001148908.1 OsmC family protein -
  AABJ83_RS22035 (VEE04_41940) crp 4501046..4501678 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AABJ83_RS22040 (VEE04_41950) yhfK 4501729..4503819 (+) 2091 WP_001309799.1 YccS/YhfK family putative transporter -
  AABJ83_RS22045 (VEE04_41960) argD 4503886..4505106 (-) 1221 WP_000190012.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AABJ83_RS22050 (VEE04_41970) pabA 4505192..4505755 (-) 564 WP_000601862.1 aminodeoxychorismate synthase component 2 -
  AABJ83_RS22055 (VEE04_41980) fic 4505787..4506389 (-) 603 WP_001280634.1 putative adenosine monophosphate-protein transferase Fic -
  AABJ83_RS22060 (VEE04_41990) yhfG 4506379..4506546 (-) 168 WP_000736851.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=87452 AABJ83_RS22035 WP_000242755.1 4501046..4501678(+) (crp) [Escherichia coli strain LR-58-2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=87452 AABJ83_RS22035 WP_000242755.1 4501046..4501678(+) (crp) [Escherichia coli strain LR-58-2]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAGGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACTGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment