Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   WJ062_RS08345 Genome accession   NZ_CP149486
Coordinates   1725318..1725914 (-) Length   198 a.a.
NCBI ID   WP_011185063.1    Uniprot ID   A2RGV1
Organism   Streptococcus pyogenes strain EMM113     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1720318..1730914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WJ062_RS08310 (WJ062_08285) - 1720378..1720683 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  WJ062_RS08315 (WJ062_08290) ruvX 1720695..1721114 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  WJ062_RS08320 (WJ062_08295) - 1721111..1721380 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  WJ062_RS08325 (WJ062_08300) spx 1721494..1721892 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  WJ062_RS08330 (WJ062_08305) recA 1722183..1723319 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  WJ062_RS08335 (WJ062_08310) cinA 1723408..1724679 (-) 1272 WP_032459984.1 competence/damage-inducible protein A Machinery gene
  WJ062_RS08340 (WJ062_08315) - 1724748..1725308 (-) 561 WP_111703697.1 DNA-3-methyladenine glycosylase I -
  WJ062_RS08345 (WJ062_08320) ruvA 1725318..1725914 (-) 597 WP_011185063.1 Holliday junction branch migration protein RuvA Machinery gene
  WJ062_RS08350 (WJ062_08325) - 1725916..1727136 (-) 1221 WP_002992187.1 MFS transporter -
  WJ062_RS08355 (WJ062_08330) hexB 1727147..1729129 (-) 1983 WP_002991363.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21852.19 Da        Isoelectric Point: 6.4948

>NTDB_id=874461 WJ062_RS08345 WP_011185063.1 1725318..1725914(-) (ruvA) [Streptococcus pyogenes strain EMM113]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=874461 WJ062_RS08345 WP_011185063.1 1725318..1725914(-) (ruvA) [Streptococcus pyogenes strain EMM113]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGGTTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.394

100

0.414