Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   WJ062_RS02450 Genome accession   NZ_CP149486
Coordinates   462224..462922 (-) Length   232 a.a.
NCBI ID   WP_085613747.1    Uniprot ID   O31050
Organism   Streptococcus pyogenes strain EMM113     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 457224..467922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WJ062_RS02425 (WJ062_02410) - 457489..457647 (+) 159 WP_002990626.1 hypothetical protein -
  WJ062_RS02430 (WJ062_02415) - 457752..457886 (+) 135 Protein_428 portal protein -
  WJ062_RS02440 (WJ062_02425) - 460114..460629 (+) 516 WP_345769885.1 helical hairpin domain-containing protein -
  WJ062_RS02445 (WJ062_02430) - 460845..462206 (-) 1362 WP_085613748.1 sensor histidine kinase KdpD -
  WJ062_RS02450 (WJ062_02435) scnR 462224..462922 (-) 699 WP_085613747.1 response regulator transcription factor Regulator
  WJ062_RS02455 (WJ062_02440) - 463120..463275 (+) 156 WP_023612114.1 lacticin 481 family lantibiotic -
  WJ062_RS02460 (WJ062_02445) - 463306..463461 (+) 156 WP_085613746.1 lacticin 481 family lantibiotic -
  WJ062_RS02465 (WJ062_02450) - 463662..463817 (+) 156 WP_023612118.1 lacticin 481 family lantibiotic -
  WJ062_RS02470 (WJ062_02455) - 463838..466621 (+) 2784 WP_136119947.1 type 2 lanthipeptide synthetase LanM family protein -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 26246.39 Da        Isoelectric Point: 6.1274

>NTDB_id=874408 WJ062_RS02450 WP_085613747.1 462224..462922(-) (scnR) [Streptococcus pyogenes strain EMM113]
MNFESQLLNKRILIVDDDVALSKSIKEVLISRDFKNISCAYSISEGIDIFSVSKIDLIILDVMLPDGEGHLLAKYIRKYS
DVPILFLTAKNNPDDEIRGLESGGDDYVTKPFLPKSLTYRIIALLRRAYKDESELIELTNCTIDLNNASVEKNGQHLSLT
PTEIQILRKLFSNKNYIASTESICDTVWGLESLGYEKSLMVHIRNIREKIEITPSKPNHLITVKGLGYKLVI

Nucleotide


Download         Length: 699 bp        

>NTDB_id=874408 WJ062_RS02450 WP_085613747.1 462224..462922(-) (scnR) [Streptococcus pyogenes strain EMM113]
ATGAATTTTGAGTCTCAATTATTGAATAAACGCATATTGATTGTCGACGATGATGTCGCACTTAGCAAATCAATTAAAGA
GGTACTTATCAGTCGGGATTTCAAGAATATCAGCTGTGCTTATAGTATAAGCGAAGGAATTGATATCTTCTCAGTTTCTA
AAATTGATCTCATTATTTTAGATGTTATGCTACCAGATGGAGAAGGGCACTTACTTGCAAAATACATTAGGAAATATTCA
GATGTGCCAATTCTCTTTTTAACAGCCAAAAACAATCCTGATGATGAAATTCGAGGACTTGAATCCGGAGGGGATGATTA
TGTTACGAAGCCATTTCTTCCCAAATCTTTAACATATCGTATTATTGCACTGTTGAGAAGGGCTTATAAAGATGAATCGG
AACTAATTGAGCTAACAAATTGTACTATAGACTTAAACAATGCAAGTGTTGAAAAAAATGGTCAACATTTGTCACTCACT
CCAACAGAAATACAAATCCTACGAAAATTATTTTCAAATAAAAATTATATTGCATCAACTGAATCGATTTGTGATACCGT
TTGGGGACTTGAGAGCCTTGGCTACGAAAAATCACTTATGGTACATATTCGTAATATCAGAGAAAAAATCGAGATAACTC
CATCTAAGCCAAATCATCTTATTACTGTAAAAGGGCTTGGTTATAAACTAGTTATATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-230)

Response regulator receiver domain (Response_reg)

(12-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O31050

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

40.948

100

0.409
  vicR Streptococcus mutans UA159

38.528

99.569

0.384
  micA Streptococcus pneumoniae Cp1015

37.826

99.138

0.375