Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RDJ18_RS05365 Genome accession   NZ_CP133442
Coordinates   1045457..1046086 (+) Length   209 a.a.
NCBI ID   WP_000153525.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SA191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1040457..1051086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDJ18_RS05340 (RDJ18_05340) - 1040836..1041822 (-) 987 WP_000999713.1 aromatic acid exporter family protein -
  RDJ18_RS05345 (RDJ18_05345) map 1042350..1043108 (+) 759 WP_000636146.1 type I methionyl aminopeptidase -
  RDJ18_RS05350 (RDJ18_05350) - 1043325..1043711 (+) 387 WP_001110179.1 hypothetical protein -
  RDJ18_RS05355 (RDJ18_05355) liaF 1043726..1044427 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  RDJ18_RS05360 (RDJ18_05360) vraS 1044424..1045467 (+) 1044 WP_001017127.1 sensor histidine kinase Regulator
  RDJ18_RS05365 (RDJ18_05365) vraR 1045457..1046086 (+) 630 WP_000153525.1 two-component system response regulator VraR Regulator
  RDJ18_RS05370 (RDJ18_05370) - 1046202..1047419 (-) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  RDJ18_RS05375 (RDJ18_05375) - 1047697..1047972 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  RDJ18_RS05380 (RDJ18_05380) - 1047979..1048443 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  RDJ18_RS05385 (RDJ18_05385) - 1048590..1048790 (+) 201 WP_000180461.1 DUF1128 family protein -
  RDJ18_RS05390 (RDJ18_05390) - 1048793..1050049 (+) 1257 WP_001795438.1 aminopeptidase -
  RDJ18_RS05395 (RDJ18_05395) - 1050139..1050669 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23572.36 Da        Isoelectric Point: 5.6942

>NTDB_id=874121 RDJ18_RS05365 WP_000153525.1 1045457..1046086(+) (vraR) [Staphylococcus aureus strain SA191]
MTIKVLFVDDHEMVRIGISSYLSKQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=874121 RDJ18_RS05365 WP_000153525.1 1045457..1046086(+) (vraR) [Staphylococcus aureus strain SA191]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAAAGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373