Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU03_RS01070 Genome accession   NZ_CP148581
Coordinates   210682..211338 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1322HEC0002     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 205682..216338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU03_RS01035 (WHU03_01035) dcyD 206562..207548 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  WHU03_RS01040 (WHU03_01040) tcyL 207563..208231 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU03_RS01045 (WHU03_01045) tcyN 208228..208980 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU03_RS01050 (WHU03_01050) sdiA 209210..209932 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  WHU03_RS01055 (WHU03_01055) yecF 209999..210223 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU03_RS01060 (WHU03_01060) yecU 210210..210386 (-) 177 WP_000590347.1 protein YecU -
  WHU03_RS01065 (WHU03_01065) - 210469..210540 (-) 72 Protein_207 transcriptional regulator -
  WHU03_RS01070 (WHU03_01070) letA 210682..211338 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU03_RS01075 (WHU03_01075) uvrC 211335..213167 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU03_RS01080 (WHU03_01080) pgsA 213224..213772 (+) 549 WP_273883237.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU03_RS01100 (WHU03_01100) yecA 214421..215086 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=873232 WHU03_RS01070 WP_000611335.1 210682..211338(+) (letA) [Escherichia coli strain Z1322HEC0002]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=873232 WHU03_RS01070 WP_000611335.1 210682..211338(+) (letA) [Escherichia coli strain Z1322HEC0002]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486