Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU61_RS13135 Genome accession   NZ_CP148573
Coordinates   2654193..2654849 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1322HEC0006     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2649193..2659849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU61_RS13105 (WHU61_13075) yecA 2650444..2651109 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  WHU61_RS13125 (WHU61_13095) pgsA 2651759..2652307 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU61_RS13130 (WHU61_13100) uvrC 2652364..2654196 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU61_RS13135 (WHU61_13105) letA 2654193..2654849 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU61_RS13140 (WHU61_13110) yecU 2655145..2655321 (+) 177 WP_000590347.1 protein YecU -
  WHU61_RS13145 (WHU61_13115) yecF 2655308..2655532 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU61_RS13150 (WHU61_13120) sdiA 2655599..2656321 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  WHU61_RS13155 (WHU61_13125) tcyN 2656551..2657303 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU61_RS13160 (WHU61_13130) tcyL 2657300..2657968 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU61_RS13165 (WHU61_13135) dcyD 2657983..2658969 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=873034 WHU61_RS13135 WP_000611335.1 2654193..2654849(-) (letA) [Escherichia coli strain Z1322HEC0006]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=873034 WHU61_RS13135 WP_000611335.1 2654193..2654849(-) (letA) [Escherichia coli strain Z1322HEC0006]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486