Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   WHU27_RS09950 Genome accession   NZ_CP148461
Coordinates   1960419..1961075 (+) Length   218 a.a.
NCBI ID   WP_000611336.1    Uniprot ID   -
Organism   Escherichia coli strain Z1323CEC0008     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1955419..1966075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU27_RS09915 (WHU27_09915) dcyD 1956298..1957284 (+) 987 WP_053263358.1 D-cysteine desulfhydrase -
  WHU27_RS09920 (WHU27_09920) tcyL 1957299..1957967 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  WHU27_RS09925 (WHU27_09925) tcyN 1957964..1958716 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  WHU27_RS09930 (WHU27_09930) sdiA 1958946..1959668 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  WHU27_RS09935 (WHU27_09935) yecF 1959736..1959960 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  WHU27_RS09940 (WHU27_09940) yecU 1959947..1960123 (-) 177 WP_000590344.1 protein YecU -
  WHU27_RS09945 (WHU27_09945) - 1960161..1960277 (-) 117 Protein_1931 transcriptional regulator -
  WHU27_RS09950 (WHU27_09950) letA 1960419..1961075 (+) 657 WP_000611336.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  WHU27_RS09955 (WHU27_09955) uvrC 1961072..1962904 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  WHU27_RS09960 (WHU27_09960) pgsA 1962961..1963509 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  WHU27_RS09980 (WHU27_09980) yecA 1964159..1964824 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23878.58 Da        Isoelectric Point: 6.6397

>NTDB_id=872277 WHU27_RS09950 WP_000611336.1 1960419..1961075(+) (letA) [Escherichia coli strain Z1323CEC0008]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITNGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=872277 WHU27_RS09950 WP_000611336.1 1960419..1961075(+) (letA) [Escherichia coli strain Z1323CEC0008]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAATGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486