Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   WHU13_RS20610 Genome accession   NZ_CP148366
Coordinates   4198487..4199119 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain Z1323HEC0300     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4193487..4204119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHU13_RS20585 (WHU13_20590) yheS 4193656..4195569 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  WHU13_RS20590 (WHU13_20595) yheT 4195569..4196591 (+) 1023 WP_000057416.1 hydrolase -
  WHU13_RS20595 (WHU13_20600) yheU 4196585..4196803 (+) 219 WP_000907085.1 YheU family protein -
  WHU13_RS20600 (WHU13_20605) prkB 4196857..4197726 (+) 870 WP_001274684.1 phosphoribulokinase -
  WHU13_RS20605 (WHU13_20610) yhfA 4197781..4198185 (-) 405 WP_001148908.1 OsmC family protein -
  WHU13_RS20610 (WHU13_20615) crp 4198487..4199119 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  WHU13_RS20615 (WHU13_20620) yhfK 4199170..4201260 (+) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  WHU13_RS20620 (WHU13_20625) argD 4201327..4202547 (-) 1221 WP_024222988.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  WHU13_RS20625 (WHU13_20630) pabA 4202633..4203196 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  WHU13_RS20630 (WHU13_20635) fic 4203228..4203830 (-) 603 WP_001280654.1 putative adenosine monophosphate-protein transferase Fic -
  WHU13_RS20635 (WHU13_20640) yhfG 4203820..4203987 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=870830 WHU13_RS20610 WP_000242755.1 4198487..4199119(+) (crp) [Escherichia coli strain Z1323HEC0300]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=870830 WHU13_RS20610 WP_000242755.1 4198487..4199119(+) (crp) [Escherichia coli strain Z1323HEC0300]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467