Detailed information
Bioinformatically predicted
Overview
| Name | amiA3 | Type | Regulator |
| Locus tag | RA106_RS06810 | Genome accession | NZ_CP132900 |
| Coordinates | 1318728..1320701 (-) | Length | 657 a.a. |
| NCBI ID | WP_011681419.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain CICC 20372 | ||
| Function | binding to XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1295154..1366186 | 1318728..1320701 | within | 0 |
| IScluster/Tn | 1317506..1326035 | 1318728..1320701 | within | 0 |
Gene organization within MGE regions
Location: 1295154..1366186
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RA106_RS06705 (RA106_06700) | liaF | 1295162..1295860 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| RA106_RS06710 (RA106_06705) | - | 1296115..1296282 (-) | 168 | WP_014608530.1 | potassium channel family protein | - |
| RA106_RS06715 (RA106_06710) | stkP/pknB | 1296920..1298791 (-) | 1872 | WP_024703938.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| RA106_RS06720 (RA106_06715) | - | 1298791..1299528 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| RA106_RS06725 (RA106_06720) | rsmB | 1299572..1300894 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| RA106_RS06730 (RA106_06725) | fmt | 1300884..1301819 (-) | 936 | WP_014608534.1 | methionyl-tRNA formyltransferase | - |
| RA106_RS06735 (RA106_06730) | - | 1301837..1304233 (-) | 2397 | WP_024703939.1 | primosomal protein N' | - |
| RA106_RS06740 (RA106_06735) | rpoZ | 1304375..1304689 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| RA106_RS06745 (RA106_06740) | gmk | 1304711..1305340 (-) | 630 | WP_014608537.1 | guanylate kinase | - |
| RA106_RS06750 (RA106_06745) | ftsY | 1305566..1306957 (-) | 1392 | WP_014608538.1 | signal recognition particle-docking protein FtsY | - |
| RA106_RS06755 (RA106_06750) | - | 1306971..1307786 (-) | 816 | WP_011226298.1 | Cof-type HAD-IIB family hydrolase | - |
| RA106_RS06760 (RA106_06755) | - | 1307779..1308573 (-) | 795 | WP_011681412.1 | HAD-IIB family hydrolase | - |
| RA106_RS06765 (RA106_06760) | - | 1308758..1309135 (+) | 378 | WP_011681413.1 | GntR family transcriptional regulator | - |
| RA106_RS06770 (RA106_06765) | - | 1309140..1309838 (+) | 699 | WP_023909821.1 | ABC transporter ATP-binding protein | - |
| RA106_RS06775 (RA106_06770) | - | 1309850..1310635 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| RA106_RS06780 (RA106_06775) | amiF | 1310685..1311614 (-) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| RA106_RS06785 (RA106_06780) | amiE | 1311607..1312692 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| RA106_RS06790 (RA106_06785) | amiD | 1312702..1313628 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| RA106_RS06795 (RA106_06790) | amiC | 1313628..1315121 (-) | 1494 | WP_011681416.1 | ABC transporter permease | Regulator |
| RA106_RS06800 (RA106_06795) | amiA | 1315183..1317150 (-) | 1968 | WP_024703940.1 | peptide ABC transporter substrate-binding protein | Regulator |
| RA106_RS06805 (RA106_06800) | - | 1317506..1318683 (+) | 1178 | Protein_1300 | ISL3 family transposase | - |
| RA106_RS06810 (RA106_06805) | amiA3 | 1318728..1320701 (-) | 1974 | WP_011681419.1 | peptide ABC transporter substrate-binding protein | Regulator |
| RA106_RS06815 (RA106_06810) | - | 1321006..1322153 (+) | 1148 | WP_095559415.1 | IS3 family transposase | - |
| RA106_RS06820 (RA106_06815) | - | 1322191..1322375 (-) | 185 | Protein_1303 | IS3 family transposase | - |
| RA106_RS06825 (RA106_06820) | - | 1322369..1322779 (-) | 411 | Protein_1304 | ATP-binding cassette domain-containing protein | - |
| RA106_RS06830 (RA106_06825) | - | 1322811..1323125 (-) | 315 | Protein_1305 | TatD family hydrolase | - |
| RA106_RS06835 (RA106_06830) | - | 1323471..1324676 (+) | 1206 | WP_011681420.1 | OFA family MFS transporter | - |
| RA106_RS06840 (RA106_06835) | - | 1324722..1326035 (-) | 1314 | Protein_1307 | IS3 family transposase | - |
| RA106_RS06845 (RA106_06840) | pta | 1326160..1327143 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| RA106_RS06850 (RA106_06845) | - | 1327157..1328053 (-) | 897 | WP_306496227.1 | RluA family pseudouridine synthase | - |
| RA106_RS06855 (RA106_06850) | - | 1328050..1328886 (-) | 837 | WP_014608552.1 | NAD kinase | - |
| RA106_RS06860 (RA106_06855) | - | 1328858..1329532 (-) | 675 | WP_011681427.1 | GTP pyrophosphokinase family protein | - |
| RA106_RS06865 (RA106_06860) | - | 1329628..1330203 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| RA106_RS06870 (RA106_06865) | - | 1330566..1331537 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| RA106_RS06875 (RA106_06870) | - | 1331541..1332653 (+) | 1113 | WP_014608554.1 | cysteine desulfurase family protein | - |
| RA106_RS06880 (RA106_06875) | - | 1332655..1333002 (+) | 348 | WP_014608555.1 | DUF1831 domain-containing protein | - |
| RA106_RS06885 (RA106_06880) | - | 1333146..1333805 (+) | 660 | WP_024703944.1 | redox-sensing transcriptional repressor Rex | - |
| RA106_RS06890 (RA106_06885) | - | 1333798..1334493 (+) | 696 | WP_024703945.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| RA106_RS06895 (RA106_06890) | radC | 1334546..1335232 (-) | 687 | WP_014727630.1 | DNA repair protein RadC | - |
| RA106_RS06900 (RA106_06895) | - | 1335281..1337065 (-) | 1785 | WP_024703946.1 | rhamnan synthesis F family protein | - |
| RA106_RS06905 (RA106_06900) | - | 1337062..1338129 (-) | 1068 | WP_024703947.1 | glycosyltransferase | - |
| RA106_RS06910 (RA106_06905) | - | 1338149..1339354 (-) | 1206 | WP_014727633.1 | ABC transporter ATP-binding protein | - |
| RA106_RS06915 (RA106_06910) | - | 1339354..1340163 (-) | 810 | WP_024703948.1 | ABC transporter permease | - |
| RA106_RS06920 (RA106_06915) | - | 1340147..1341103 (-) | 957 | WP_024703949.1 | glycosyltransferase family 2 protein | - |
| RA106_RS06925 (RA106_06920) | cps2T | 1341100..1342248 (-) | 1149 | WP_024703950.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| RA106_RS06930 (RA106_06925) | - | 1342355..1343896 (-) | 1542 | WP_024703951.1 | DUF2142 domain-containing protein | - |
| RA106_RS06935 (RA106_06930) | - | 1343903..1344913 (-) | 1011 | WP_024703952.1 | glycosyltransferase | - |
| RA106_RS06940 (RA106_06935) | - | 1344913..1346187 (-) | 1275 | WP_024703953.1 | lipopolysaccharide biosynthesis protein | - |
| RA106_RS06945 (RA106_06940) | - | 1346180..1346512 (-) | 333 | WP_011226332.1 | DUF2304 domain-containing protein | - |
| RA106_RS06950 (RA106_06945) | - | 1346518..1347213 (-) | 696 | WP_024703954.1 | glycosyltransferase family 2 protein | - |
| RA106_RS06955 (RA106_06950) | rfbD | 1347290..1348141 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| RA106_RS06960 (RA106_06955) | - | 1348218..1349552 (-) | 1335 | WP_024703955.1 | DUF6056 family protein | - |
| RA106_RS06965 (RA106_06960) | - | 1349665..1350591 (-) | 927 | WP_024703956.1 | glycosyltransferase family 2 protein | - |
| RA106_RS06970 (RA106_06965) | - | 1350601..1350936 (-) | 336 | WP_024703957.1 | metal-sulfur cluster assembly factor | - |
| RA106_RS06975 (RA106_06970) | rpoD | 1350990..1352099 (-) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| RA106_RS06980 (RA106_06975) | dnaG | 1352103..1353914 (-) | 1812 | WP_024703958.1 | DNA primase | - |
| RA106_RS06985 (RA106_06980) | mscL | 1354057..1354137 (+) | 81 | Protein_1336 | large conductance mechanosensitive channel protein MscL | - |
| RA106_RS06990 (RA106_06985) | rpsU | 1354297..1354473 (-) | 177 | WP_011681449.1 | 30S ribosomal protein S21 | - |
| RA106_RS06995 (RA106_06990) | - | 1354667..1355461 (-) | 795 | WP_023909836.1 | ABC transporter substrate-binding protein | - |
| RA106_RS07000 (RA106_06995) | - | 1355523..1356632 (-) | 1110 | WP_024703959.1 | aminotransferase | - |
| RA106_RS07005 (RA106_07000) | - | 1356980..1357777 (-) | 798 | WP_014621828.1 | transporter substrate-binding domain-containing protein | - |
| RA106_RS07010 (RA106_07005) | - | 1357774..1358604 (-) | 831 | WP_014621829.1 | transporter substrate-binding domain-containing protein | - |
| RA106_RS07015 (RA106_07010) | - | 1358818..1359282 (-) | 465 | WP_011681454.1 | 8-oxo-dGTP diphosphatase | - |
| RA106_RS07020 (RA106_07015) | uvrB | 1359327..1361318 (-) | 1992 | WP_014608579.1 | excinuclease ABC subunit UvrB | - |
| RA106_RS07025 (RA106_07020) | - | 1361465..1361932 (-) | 468 | WP_014608580.1 | hypothetical protein | - |
| RA106_RS07030 (RA106_07025) | - | 1362005..1362941 (-) | 937 | Protein_1345 | CPBP family intramembrane glutamic endopeptidase | - |
| RA106_RS07035 (RA106_07030) | - | 1363140..1365349 (+) | 2210 | Protein_1346 | ABC transporter substrate-binding protein/permease | - |
| RA106_RS07040 (RA106_07035) | - | 1365349..1366089 (+) | 741 | WP_024703961.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 657 a.a. Molecular weight: 72221.23 Da Isoelectric Point: 5.1726
>NTDB_id=870558 RA106_RS06810 WP_011681419.1 1318728..1320701(-) (amiA3) [Streptococcus thermophilus strain CICC 20372]
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDDYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIFYTAPGASTSAIGINIDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLGVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNL
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVNQSSKLNVAQVQSLKQTIEKSLGSENVVIDINQLSSDDLEN
ATLNAANAAAEDWDISNSVGWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPVISRLTPFTGASLQVGDKNSSNDYIKYVKPQEKVVTKKEYEQSREKWLKE
KKESNEKAQKDLEKHVK
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDDYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIFYTAPGASTSAIGINIDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLGVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNL
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVNQSSKLNVAQVQSLKQTIEKSLGSENVVIDINQLSSDDLEN
ATLNAANAAAEDWDISNSVGWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPVISRLTPFTGASLQVGDKNSSNDYIKYVKPQEKVVTKKEYEQSREKWLKE
KKESNEKAQKDLEKHVK
Nucleotide
Download Length: 1974 bp
>NTDB_id=870558 RA106_RS06810 WP_011681419.1 1318728..1320701(-) (amiA3) [Streptococcus thermophilus strain CICC 20372]
ATGAAAAAAAGCAAATGGTTGGCCCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTACGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGACTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATCAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACAAGTTCAAACTATGCTTCTGTAGAAAAAAAATATAAAGATAATATTTTTT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATATTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGGTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATCTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTAACCAAAGCTCTAAACTTAATGTTGCCCAAGTCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GCAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGGTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCTTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGTTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAAAACTCATCAAACGACT
ACATCAAATATGTGAAACCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAA
AAGAAAGAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
ATGAAAAAAAGCAAATGGTTGGCCCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTACGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGACTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATCAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACAAGTTCAAACTATGCTTCTGTAGAAAAAAAATATAAAGATAATATTTTTT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATATTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGGTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATCTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTAACCAAAGCTCTAAACTTAATGTTGCCCAAGTCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GCAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGGTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCTTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGTTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAAAACTCATCAAACGACT
ACATCAAATATGTGAAACCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAA
AAGAAAGAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiA3 | Streptococcus thermophilus LMD-9 |
100 |
100 |
1 |
| amiA3 | Streptococcus thermophilus LMG 18311 |
98.478 |
100 |
0.985 |
| amiA | Streptococcus salivarius strain HSISS4 |
90.411 |
100 |
0.904 |