Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AABJ73_RS22415 Genome accession   NZ_AP027520
Coordinates   4562373..4563005 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain LR-31     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4557373..4568005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ73_RS22390 (VEE27_43170) yheS 4557542..4559455 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AABJ73_RS22395 (VEE27_43180) yheT 4559455..4560477 (+) 1023 WP_072721322.1 hydrolase -
  AABJ73_RS22400 (VEE27_43190) yheU 4560471..4560689 (+) 219 WP_000907085.1 YheU family protein -
  AABJ73_RS22405 (VEE27_43200) prkB 4560743..4561612 (+) 870 WP_001274680.1 phosphoribulokinase -
  AABJ73_RS22410 (VEE27_43210) yhfA 4561667..4562071 (-) 405 WP_001148908.1 OsmC family protein -
  AABJ73_RS22415 (VEE27_43220) crp 4562373..4563005 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AABJ73_RS22420 (VEE27_43230) yhfK 4563056..4565146 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AABJ73_RS22425 (VEE27_43240) argD 4565213..4566433 (-) 1221 WP_058905623.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AABJ73_RS22430 (VEE27_43250) pabA 4566519..4567082 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AABJ73_RS22435 (VEE27_43260) fic 4567114..4567716 (-) 603 WP_000502522.1 putative adenosine monophosphate-protein transferase Fic -
  AABJ73_RS22440 (VEE27_43270) yhfG 4567706..4567873 (-) 168 WP_000736861.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=86894 AABJ73_RS22415 WP_000242755.1 4562373..4563005(+) (crp) [Escherichia coli strain LR-31]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=86894 AABJ73_RS22415 WP_000242755.1 4562373..4563005(+) (crp) [Escherichia coli strain LR-31]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment