Detailed information NTG0868638

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RAM31_RS10870
• Genome accession: NZ_CP132368
• Coordinates: 2266919..2267962 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UNC_SA44
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2261919..2272962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RAM31_RS10840 (RAM31_10835)	-	2262347..2263603 (-)	1257	WP_001793428.1	aminopeptidase	-
RAM31_RS10845 (RAM31_10840)	-	2263606..2263806 (-)	201	WP_000180460.1	DUF1128 family protein	-
RAM31_RS10850 (RAM31_10845)	-	2263953..2264417 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RAM31_RS10855 (RAM31_10850)	-	2264424..2264699 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RAM31_RS10860 (RAM31_10855)	-	2264977..2266188 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
RAM31_RS10865 (RAM31_10860)	vraR	2266300..2266929 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RAM31_RS10870 (RAM31_10865)	vraS	2266919..2267962 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RAM31_RS10875 (RAM31_10870)	liaF	2267959..2268660 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RAM31_RS10880 (RAM31_10875)	-	2268675..2269061 (-)	387	WP_001110179.1	hypothetical protein	-
RAM31_RS10885 (RAM31_10880)	map	2269278..2270036 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RAM31_RS10890 (RAM31_10885)	-	2270567..2271553 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
RAM31_RS10895 (RAM31_10890)	-	2271984..2272397 (-)	414	WP_001837236.1	hypothetical protein	-
RAM31_RS10900 (RAM31_10895)	-	2272426..2272537 (-)	112	Protein_2119	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=868638 RAM31_RS10870 WP_001017131.1 2266919..2267962(-) (vraS) [Staphylococcus aureus strain UNC_SA44]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=868638 RAM31_RS10870 WP_001017131.1 2266919..2267962(-) (vraS) [Staphylococcus aureus strain UNC_SA44]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTAAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1