Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RAM31_RS11285 Genome accession   NZ_CP132368
Coordinates   2346416..2347132 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain UNC_SA44     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2341416..2352132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM31_RS11255 (RAM31_11255) - 2341632..2342258 (+) 627 WP_000522384.1 nitroreductase family protein -
  RAM31_RS11260 (RAM31_11260) - 2342619..2343404 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  RAM31_RS11265 (RAM31_11265) hld 2344003..2344083 (-) 81 WP_000046023.1 delta-hemolysin -
  RAM31_RS11270 (RAM31_11270) - 2344373..2344936 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  RAM31_RS11275 (RAM31_11275) agrD 2344940..2345080 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  RAM31_RS11280 (RAM31_11280) agrC 2345105..2346397 (+) 1293 WP_306178646.1 quorum-sensing sensor histidine kinase AgrC -
  RAM31_RS11285 (RAM31_11285) agrA 2346416..2347132 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  RAM31_RS11290 (RAM31_11290) - 2347204..2347313 (+) 110 Protein_2197 hypothetical protein -
  RAM31_RS11295 (RAM31_11295) - 2347501..2348460 (-) 960 WP_001253302.1 carbohydrate kinase -
  RAM31_RS11300 (RAM31_11300) - 2348457..2349941 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  RAM31_RS11305 (RAM31_11305) - 2350090..2351040 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=868639 RAM31_RS11285 WP_000688492.1 2346416..2347132(+) (agrA) [Staphylococcus aureus strain UNC_SA44]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=868639 RAM31_RS11285 WP_000688492.1 2346416..2347132(+) (agrA) [Staphylococcus aureus strain UNC_SA44]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1