Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   WHO38_RS18995 Genome accession   NZ_CP148124
Coordinates   3611679..3613664 (-) Length   661 a.a.
NCBI ID   WP_003243787.1    Uniprot ID   P37954
Organism   Bacillus subtilis isolate FELIX_MS521     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3606679..3618664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO38_RS18975 yvlA 3607181..3607507 (-) 327 WP_003244375.1 protein YvlA -
  WHO38_RS18980 - 3607725..3607955 (+) 231 WP_003228059.1 hypothetical protein -
  WHO38_RS18985 - 3608154..3608717 (-) 564 Protein_3679 flagellin -
  WHO38_RS18990 uvrA 3608798..3611671 (-) 2874 WP_003228057.1 excinuclease ABC subunit UvrA Machinery gene
  WHO38_RS18995 uvrB 3611679..3613664 (-) 1986 WP_003243787.1 excinuclease ABC subunit UvrB Machinery gene
  WHO38_RS19000 csbA 3613850..3614080 (-) 231 WP_003228053.1 CsbA family protein -
  WHO38_RS19005 yvkC 3614527..3617022 (+) 2496 WP_003243243.1 PEP/pyruvate-binding domain-containing protein -
  WHO38_RS19010 yvkB 3617098..3617667 (+) 570 WP_003244088.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76327.13 Da        Isoelectric Point: 5.2528

>NTDB_id=865633 WHO38_RS18995 WP_003243787.1 3611679..3613664(-) (uvrB) [Bacillus subtilis isolate FELIX_MS521]
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGS
TPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYE
IEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSM
EIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAK
ALDFERAAELRDLLLELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=865633 WHO38_RS18995 WP_003243787.1 3611679..3613664(-) (uvrB) [Bacillus subtilis isolate FELIX_MS521]
GTGAAAGATCGCTTTGAGTTAGTCTCGAAATATCAGCCCCAGGGAGATCAGCCGAAAGCCATTGAAAAGCTTGTGAAAGG
AATTCAGGAGGGCAAGAAGCATCAGACTCTGCTGGGTGCAACAGGAACTGGGAAAACATTTACGGTGTCCAATTTGATTA
AAGAAGTCAATAAGCCGACTCTCGTGATTGCCCATAACAAAACCCTTGCTGGACAGCTTTACAGTGAGTTCAAGGAATTT
TTTCCGAACAATGCTGTCGAGTATTTTGTCAGCTACTATGATTATTATCAGCCGGAGGCGTATGTGCCTCAAACGGATAC
ATTTATAGAGAAAGACGCTAGTATTAATGATGAAATTGATAAACTGAGACACTCCGCCACATCAGCTTTGTTTGAGCGCA
GAGATGTCATTATTATTGCGAGTGTGTCTTGTATATACGGCCTCGGTTCGCCTGAGGAATACCGGGAAATGGTCGTGTCA
CTGCGGACTGAAATGGAAATTGAGCGCAACGAGCTGCTCAGAAAACTTGTAGACATCCAATATGCCCGCAACGATATCGA
CTTTCAGCGCGGTACATTTCGTGTGCGCGGGGATGTAGTGGAAATCTTTCCGGCATCCCGTGATGAGCATTGTGTCAGAG
TTGAATTTTTCGGTGACGAAATCGAACGGATTCGGGAAGTAGATGCGCTGACAGGAGAAATTCTCGGCGACCGAGATCAT
GTTGCGATTTTCCCGGCATCCCACTTCGTAACGCGGGCCGAGAAAATGGAGAAGGCGATTCAAAATATCGAGAAGGAGCT
TGAGGAGCAGCTGAAGGTCATGCATGAAAACGGAAAGCTCCTTGAAGCGCAGCGTTTAGAGCAGCGGACAAGATATGATC
TTGAAATGATGCGTGAAATGGGTTTCTGCTCCGGCATCGAGAACTATTCAAGACATTTGACTCTGCGGCCTCCAGGTTCA
ACGCCGTATACGCTTCTTGATTATTTCCCAGACGATTTTATGATCGTGGTGGATGAGTCGCATGTGACAATTCCTCAGGT
GCGCGGCATGTTTAACGGAGACCAGGCGCGGAAACAGGTGCTCGTGGATCACGGCTTCCGGCTTCCATCAGCGCTTGATA
ACCGTCCGCTTCGTTTTGAGGAATTTGAAAAGCATATGCACAATATCGTGTATGTATCAGCAACACCAGGGCCGTACGAG
ATTGAACATACAGATGAAATGGTCGAACAGATCATTCGTCCGACGGGGCTTCTTGACCCGCTTATTGACGTCCGTCCAAT
CGAAGGTCAGATTGACGACTTGATCGGCGAAATTCAAGCAAGAATCGAGCGGAATGAACGGGTGCTTGTGACAACTTTGA
CGAAGAAGATGTCAGAGGATCTGACCGATTATTTAAAGGAAATCGGCATTAAAGTAAACTATCTGCATTCTGAGATCAAG
ACGCTTGAACGGATTGAAATTATCCGCGACCTGCGCCTTGGCAAGTACGATGTGCTTGTCGGCATCAACCTGCTGAGGGA
AGGTTTGGACATTCCCGAAGTATCCCTTGTTGCGATTTTGGATGCGGATAAGGAAGGTTTCCTTCGTTCGGAGCGGTCGC
TGATCCAGACCATCGGACGGGCAGCGAGAAATGCGGAAGGCCGCGTCATTATGTACGCCGATAAAATAACGAAGTCTATG
GAAATTGCGATTAATGAAACAAAACGCCGCCGCGAGCAGCAGGAGCGGTTTAACGAAGAGCACGGCATTACGCCGAAAAC
GATAAATAAAGAAATTCGCGATGTCATTCGTGCCACAGTAGCAGCTGAGGATAAAGCGGAATACAAAACAAAAGCCGCGC
CGAAGCTGTCGAAAATGACGAAGAAAGAACGCCAGAAAGTCGTTGAACAGATGGAGCATGAAATGAAGGAAGCCGCCAAG
GCGCTTGACTTTGAGAGAGCCGCGGAGCTTCGCGATTTACTTTTAGAGCTAAAAGCGGAAGGATGA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(12-138)

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(626-659)

Helicase conserved C-terminal domain (Helicase_C)

(440-544)

Ultra-violet resistance protein B (UvrB)

(551-593)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2D7D
  PDB 2NMV
  PDB 3V4R

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

70.561

99.697

0.703
  uvrB Streptococcus pneumoniae R6

70.41

99.697

0.702
  uvrB Streptococcus pneumoniae D39

70.41

99.697

0.702