Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7611_RS04010 Genome accession   NZ_CP131723
Coordinates   784471..785691 (+) Length   406 a.a.
NCBI ID   WP_005666687.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018C08-260     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 779471..790691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7611_RS03990 (Q7611_03990) corC 780437..781336 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  Q7611_RS03995 (Q7611_03995) ampD 781959..782519 (-) 561 WP_075985522.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  Q7611_RS04000 (Q7611_04000) pilA 782634..783083 (+) 450 WP_005666683.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  Q7611_RS04005 (Q7611_04005) pilB 783080..784474 (+) 1395 WP_005666685.1 GspE/PulE family protein Machinery gene
  Q7611_RS04010 (Q7611_04010) pilC 784471..785691 (+) 1221 WP_005666687.1 type II secretion system F family protein Machinery gene
  Q7611_RS04015 (Q7611_04015) pilD 785688..786380 (+) 693 WP_075985521.1 A24 family peptidase Machinery gene
  Q7611_RS04020 (Q7611_04020) rho 786435..787697 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  Q7611_RS04025 (Q7611_04025) metJ 787945..788262 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  Q7611_RS04030 (Q7611_04030) cueR 788276..788662 (-) 387 WP_038439225.1 Cu(I)-responsive transcriptional regulator -
  Q7611_RS04035 (Q7611_04035) - 788739..788945 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  Q7611_RS04040 (Q7611_04040) - 789031..789237 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46207.43 Da        Isoelectric Point: 9.8218

>NTDB_id=864800 Q7611_RS04010 WP_005666687.1 784471..785691(+) (pilC) [Haemophilus influenzae strain 2018C08-260]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMVYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQQKNQLISVTPIFGTIQKLSRLVNFSRSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=864800 Q7611_RS04010 WP_005666687.1 784471..785691(+) (pilC) [Haemophilus influenzae strain 2018C08-260]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCGCACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGGTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGTTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCGCAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTTTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379