Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   Q7616_RS00190 Genome accession   NZ_CP131717
Coordinates   40918..41592 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 2016N21-284     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 35918..46592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7616_RS00170 (Q7616_00170) hinT 37612..37962 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  Q7616_RS00175 (Q7616_00175) - 37962..38312 (+) 351 WP_005647993.1 DUF1425 domain-containing protein -
  Q7616_RS00180 (Q7616_00180) nagZ 38316..39368 (+) 1053 WP_118806416.1 beta-N-acetylhexosaminidase -
  Q7616_RS00185 (Q7616_00185) rlmC 39365..40561 (+) 1197 WP_342120205.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  Q7616_RS00190 (Q7616_00190) crp 40918..41592 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  Q7616_RS00195 (Q7616_00195) - 41577..41828 (-) 252 WP_005647999.1 YheU family protein -
  Q7616_RS00200 (Q7616_00200) slmA 41850..42506 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  Q7616_RS00205 (Q7616_00205) dut 42510..42965 (-) 456 WP_005631431.1 dUTP diphosphatase -
  Q7616_RS00210 (Q7616_00210) coaBC 43013..44215 (-) 1203 WP_118806414.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  Q7616_RS00215 (Q7616_00215) radC 44379..45044 (+) 666 WP_105894713.1 DNA repair protein RadC -
  Q7616_RS00220 (Q7616_00220) rpmB 45258..45494 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  Q7616_RS00225 (Q7616_00225) rpmG 45506..45676 (+) 171 WP_005648006.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=864593 Q7616_RS00190 WP_005647998.1 40918..41592(-) (crp) [Haemophilus influenzae strain 2016N21-284]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=864593 Q7616_RS00190 WP_005647998.1 40918..41592(-) (crp) [Haemophilus influenzae strain 2016N21-284]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCGGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42