Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   Q7617_RS00175 Genome accession   NZ_CP131716
Coordinates   39546..40220 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain 2016C10-304     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34546..45220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7617_RS00155 (Q7617_00155) hinT 36251..36601 (+) 351 WP_005669644.1 purine nucleoside phosphoramidase -
  Q7617_RS00160 (Q7617_00160) - 36601..36951 (+) 351 WP_005647993.1 DUF1425 domain-containing protein -
  Q7617_RS00165 (Q7617_00165) nagZ 36955..38010 (+) 1056 WP_105893778.1 beta-N-acetylhexosaminidase -
  Q7617_RS00170 (Q7617_00170) rlmC 38003..39181 (+) 1179 WP_112119051.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  Q7617_RS00175 (Q7617_00175) crp 39546..40220 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  Q7617_RS00180 (Q7617_00180) - 40205..40456 (-) 252 WP_005647999.1 YheU family protein -
  Q7617_RS00185 (Q7617_00185) slmA 40478..41134 (-) 657 WP_061723804.1 nucleoid occlusion factor SlmA -
  Q7617_RS00190 (Q7617_00190) dut 41138..41593 (-) 456 WP_005631431.1 dUTP diphosphatase -
  Q7617_RS00195 (Q7617_00195) coaBC 41641..42843 (-) 1203 WP_126513381.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  Q7617_RS00200 (Q7617_00200) radC 43007..43672 (+) 666 WP_020910156.1 DNA repair protein RadC -
  Q7617_RS00205 (Q7617_00205) rpmB 43886..44122 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  Q7617_RS00210 (Q7617_00210) rpmG 44134..44304 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=864556 Q7617_RS00175 WP_005647998.1 39546..40220(-) (crp) [Haemophilus influenzae strain 2016C10-304]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=864556 Q7617_RS00175 WP_005647998.1 39546..40220(-) (crp) [Haemophilus influenzae strain 2016C10-304]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTGACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42