Detailed information NTG0864531

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7618_RS09730
• Genome accession: NZ_CP131715
• Coordinates: 1882761..1883771 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2006C08-243
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1877761..1888771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7618_RS09705 (Q7618_09680)	-	1878926..1879220 (-)	295	Protein_1899	hypothetical protein	-
Q7618_RS09710 (Q7618_09685)	-	1879382..1879834 (+)	453	WP_000079148.1	universal stress protein	-
Q7618_RS09715 (Q7618_09690)	-	1879869..1881257 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
Q7618_RS09720 (Q7618_09695)	-	1881323..1882285 (+)	963	WP_001124786.1	asparaginase	-
Q7618_RS09725 (Q7618_09700)	-	1882314..1882697 (-)	384	WP_001092022.1	hypothetical protein	-
Q7618_RS09730 (Q7618_09705)	ccpA	1882761..1883771 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7618_RS09735 (Q7618_09710)	-	1884196..1884795 (-)	600	WP_000866703.1	response regulator transcription factor	-
Q7618_RS09740 (Q7618_09715)	-	1884796..1885893 (-)	1098	WP_000893503.1	sensor histidine kinase	-
Q7618_RS09745 (Q7618_09720)	-	1885893..1886630 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7618_RS09750 (Q7618_09725)	-	1886632..1887516 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
Q7618_RS09755 (Q7618_09730)	-	1887503..1887697 (-)	195	WP_000715302.1	hypothetical protein	-
Q7618_RS09760 (Q7618_09735)	-	1887694..1887900 (-)	207	Protein_1910	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=864531 Q7618_RS09730 WP_000990607.1 1882761..1883771(-) (ccpA) [Streptococcus pneumoniae strain 2006C08-243]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=864531 Q7618_RS09730 WP_000990607.1 1882761..1883771(-) (ccpA) [Streptococcus pneumoniae strain 2006C08-243]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568