Detailed information NTG0864458

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: Q7619_RS10075
• Genome accession: NZ_CP131714
• Coordinates: 1939985..1940287 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2008C04-309
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1934985..1945287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7619_RS10040 (Q7619_10010)	rnpA	1935667..1936038 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7619_RS10045 (Q7619_10015)	-	1936055..1936186 (-)	132	WP_000768904.1	hypothetical protein	-
Q7619_RS10050 (Q7619_10020)	-	1936187..1937377 (-)	1191	WP_000167765.1	acetate kinase	-
Q7619_RS10055 (Q7619_10025)	comYH	1937428..1938381 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
Q7619_RS10060 (Q7619_10030)	-	1938442..1939034 (-)	593	Protein_1956	methyltransferase domain-containing protein	-
Q7619_RS10065 (Q7619_10035)	comGG/cglG	1939137..1939583 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7619_RS10070 (Q7619_10040)	comGF/cglF	1939561..1940022 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7619_RS10075 (Q7619_10045)	comGE/cglE	1939985..1940287 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7619_RS10080 (Q7619_10050)	comGD/cglD	1940250..1940684 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7619_RS10085 (Q7619_10055)	comGC/cglC	1940647..1940970 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
Q7619_RS10090 (Q7619_10060)	comGB/cglB	1940972..1941988 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7619_RS10095 (Q7619_10065)	comGA/cglA/cilD	1941936..1942877 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7619_RS10100 (Q7619_10070)	-	1942953..1943318 (-)	366	WP_054407367.1	DUF1033 family protein	-
Q7619_RS10105 (Q7619_10075)	-	1943469..1944527 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=864458 Q7619_RS10075 WP_000413382.1 1939985..1940287(-) (comGE/cglE) [Streptococcus pneumoniae strain 2008C04-309]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=864458 Q7619_RS10075 WP_000413382.1 1939985..1940287(-) (comGE/cglE) [Streptococcus pneumoniae strain 2008C04-309]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4