Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   Q7619_RS10090 Genome accession   NZ_CP131714
Coordinates   1940972..1941988 (-) Length   338 a.a.
NCBI ID   WP_078130737.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2008C04-309     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1935972..1946988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7619_RS10045 (Q7619_10015) - 1936055..1936186 (-) 132 WP_000768904.1 hypothetical protein -
  Q7619_RS10050 (Q7619_10020) - 1936187..1937377 (-) 1191 WP_000167765.1 acetate kinase -
  Q7619_RS10055 (Q7619_10025) comYH 1937428..1938381 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  Q7619_RS10060 (Q7619_10030) - 1938442..1939034 (-) 593 Protein_1956 methyltransferase domain-containing protein -
  Q7619_RS10065 (Q7619_10035) comGG/cglG 1939137..1939583 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  Q7619_RS10070 (Q7619_10040) comGF/cglF 1939561..1940022 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  Q7619_RS10075 (Q7619_10045) comGE/cglE 1939985..1940287 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  Q7619_RS10080 (Q7619_10050) comGD/cglD 1940250..1940684 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  Q7619_RS10085 (Q7619_10055) comGC/cglC 1940647..1940970 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  Q7619_RS10090 (Q7619_10060) comGB/cglB 1940972..1941988 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  Q7619_RS10095 (Q7619_10065) comGA/cglA/cilD 1941936..1942877 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  Q7619_RS10100 (Q7619_10070) - 1942953..1943318 (-) 366 WP_054407367.1 DUF1033 family protein -
  Q7619_RS10105 (Q7619_10075) - 1943469..1944527 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  Q7619_RS10110 (Q7619_10080) nagA 1944690..1945841 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38523.66 Da        Isoelectric Point: 9.8240

>NTDB_id=864461 Q7619_RS10090 WP_078130737.1 1940972..1941988(-) (comGB/cglB) [Streptococcus pneumoniae strain 2008C04-309]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMKSLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=864461 Q7619_RS10090 WP_078130737.1 1940972..1941988(-) (comGB/cglB) [Streptococcus pneumoniae strain 2008C04-309]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGAAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTCCATGGTAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATTTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae D39

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae R6

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae TIGR4

98.817

100

0.988
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5