Detailed information NTG0864452

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7619_RS09765
• Genome accession: NZ_CP131714
• Coordinates: 1890740..1891750 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2008C04-309
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1885740..1896750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7619_RS09740 (Q7619_09710)	-	1886905..1887199 (-)	295	Protein_1906	hypothetical protein	-
Q7619_RS09745 (Q7619_09715)	-	1887361..1887813 (+)	453	WP_000079148.1	universal stress protein	-
Q7619_RS09750 (Q7619_09720)	-	1887848..1889236 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
Q7619_RS09755 (Q7619_09725)	-	1889302..1890264 (+)	963	WP_001124786.1	asparaginase	-
Q7619_RS09760 (Q7619_09730)	-	1890293..1890676 (-)	384	WP_001092022.1	hypothetical protein	-
Q7619_RS09765 (Q7619_09735)	ccpA	1890740..1891750 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7619_RS09770 (Q7619_09740)	-	1892175..1892774 (-)	600	WP_000866703.1	response regulator transcription factor	-
Q7619_RS09775 (Q7619_09745)	-	1892775..1893872 (-)	1098	WP_000893503.1	sensor histidine kinase	-
Q7619_RS09780 (Q7619_09750)	-	1893872..1894609 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7619_RS09785 (Q7619_09755)	-	1894611..1895495 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
Q7619_RS09790 (Q7619_09760)	-	1895482..1895676 (-)	195	WP_000715302.1	hypothetical protein	-
Q7619_RS09795 (Q7619_09765)	-	1895673..1895879 (-)	207	Protein_1917	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=864452 Q7619_RS09765 WP_000990607.1 1890740..1891750(-) (ccpA) [Streptococcus pneumoniae strain 2008C04-309]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=864452 Q7619_RS09765 WP_000990607.1 1890740..1891750(-) (ccpA) [Streptococcus pneumoniae strain 2008C04-309]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568