Detailed information NTG0864373

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7620_RS09755
• Genome accession: NZ_CP131713
• Coordinates: 1889901..1890911 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2008C09-276
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1884901..1895911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7620_RS09730 (Q7620_09700)	-	1886066..1886360 (-)	295	Protein_1904	hypothetical protein	-
Q7620_RS09735 (Q7620_09705)	-	1886522..1886974 (+)	453	WP_000079148.1	universal stress protein	-
Q7620_RS09740 (Q7620_09710)	-	1887009..1888397 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
Q7620_RS09745 (Q7620_09715)	-	1888463..1889425 (+)	963	WP_001124786.1	asparaginase	-
Q7620_RS09750 (Q7620_09720)	-	1889454..1889837 (-)	384	WP_001092022.1	hypothetical protein	-
Q7620_RS09755 (Q7620_09725)	ccpA	1889901..1890911 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7620_RS09760 (Q7620_09730)	-	1891336..1891935 (-)	600	WP_000866703.1	response regulator transcription factor	-
Q7620_RS09765 (Q7620_09735)	-	1891936..1893033 (-)	1098	WP_000893503.1	sensor histidine kinase	-
Q7620_RS09770 (Q7620_09740)	-	1893033..1893770 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7620_RS09775 (Q7620_09745)	-	1893772..1894656 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
Q7620_RS09780 (Q7620_09750)	-	1894643..1894837 (-)	195	WP_000715302.1	hypothetical protein	-
Q7620_RS09785 (Q7620_09755)	-	1894834..1895040 (-)	207	Protein_1915	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=864373 Q7620_RS09755 WP_000990607.1 1889901..1890911(-) (ccpA) [Streptococcus pneumoniae strain 2008C09-276]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=864373 Q7620_RS09755 WP_000990607.1 1889901..1890911(-) (ccpA) [Streptococcus pneumoniae strain 2008C09-276]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568