Detailed information NTG0864294

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7621_RS09680
• Genome accession: NZ_CP131712
• Coordinates: 1946853..1947863 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2008C09-280
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1941853..1952863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7621_RS09655 (Q7621_09650)	-	1941919..1943133 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
Q7621_RS09660 (Q7621_09655)	-	1943289..1943582 (-)	294	WP_000977368.1	hypothetical protein	-
Q7621_RS09665 (Q7621_09660)	-	1943744..1944196 (+)	453	WP_000079148.1	universal stress protein	-
Q7621_RS09670 (Q7621_09665)	-	1944231..1945619 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
Q7621_RS09675 (Q7621_09670)	-	1945685..1946647 (+)	963	WP_001124777.1	asparaginase	-
Q7621_RS09680 (Q7621_09675)	ccpA	1946853..1947863 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7621_RS09685 (Q7621_09680)	-	1948288..1948887 (-)	600	WP_000866719.1	response regulator transcription factor	-
Q7621_RS09690 (Q7621_09685)	-	1948889..1949986 (-)	1098	WP_000893500.1	sensor histidine kinase	-
Q7621_RS09695 (Q7621_09690)	-	1949986..1950723 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7621_RS09700 (Q7621_09695)	-	1950725..1951609 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
Q7621_RS09705 (Q7621_09700)	-	1951596..1951790 (-)	195	WP_000820189.1	hypothetical protein	-
Q7621_RS09710 (Q7621_09705)	-	1951787..1951993 (-)	207	Protein_1901	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=864294 Q7621_RS09680 WP_000990607.1 1946853..1947863(-) (ccpA) [Streptococcus pneumoniae strain 2008C09-280]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=864294 Q7621_RS09680 WP_000990607.1 1946853..1947863(-) (ccpA) [Streptococcus pneumoniae strain 2008C09-280]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568