Detailed information NTG0864222

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: Q7622_RS09685
• Genome accession: NZ_CP131711
• Coordinates: 1884480..1884941 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250545.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2014C08-275
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1879480..1889941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7622_RS09650 (Q7622_09620)	-	1879791..1880615 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
Q7622_RS09655 (Q7622_09625)	rnpA	1880590..1880961 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7622_RS09660 (Q7622_09630)	-	1880978..1881109 (-)	132	WP_000768904.1	hypothetical protein	-
Q7622_RS09665 (Q7622_09635)	-	1881110..1882300 (-)	1191	WP_000167766.1	acetate kinase	-
Q7622_RS09670 (Q7622_09640)	comYH	1882351..1883304 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
Q7622_RS09675 (Q7622_09645)	-	1883365..1883952 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
Q7622_RS09680 (Q7622_09650)	comGG/cglG	1884089..1884502 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7622_RS09685 (Q7622_09655)	comGF/cglF	1884480..1884941 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7622_RS09690 (Q7622_09660)	comGE/cglE	1884904..1885206 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7622_RS09695 (Q7622_09665)	comGD/cglD	1885169..1885573 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7622_RS09700 (Q7622_09670)	comGC/cglC	1885566..1885892 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
Q7622_RS09705 (Q7622_09675)	comGB/cglB	1885894..1886910 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7622_RS09710 (Q7622_09680)	comGA/cglA/cilD	1886858..1887799 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7622_RS09715 (Q7622_09685)	-	1887875..1888240 (-)	366	WP_000286415.1	DUF1033 family protein	-
Q7622_RS09720 (Q7622_09690)	-	1888391..1889449 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17855.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=864222 Q7622_RS09685 WP_000250545.1 1884480..1884941(-) (comGF/cglF) [Streptococcus pneumoniae strain 2014C08-275]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=864222 Q7622_RS09685 WP_000250545.1 1884480..1884941(-) (comGF/cglF) [Streptococcus pneumoniae strain 2014C08-275]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915