Detailed information NTG0864141

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7623_RS09765
• Genome accession: NZ_CP131710
• Coordinates: 1883501..1884511 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2014S11-203
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1878501..1889511

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7623_RS09740 (Q7623_09705)	-	1879666..1879960 (-)	295	Protein_1907	hypothetical protein	-
Q7623_RS09745 (Q7623_09710)	-	1880122..1880574 (+)	453	WP_000079148.1	universal stress protein	-
Q7623_RS09750 (Q7623_09715)	-	1880609..1881997 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
Q7623_RS09755 (Q7623_09720)	-	1882063..1883025 (+)	963	WP_001124786.1	asparaginase	-
Q7623_RS09760 (Q7623_09725)	-	1883054..1883437 (-)	384	WP_001092022.1	hypothetical protein	-
Q7623_RS09765 (Q7623_09730)	ccpA	1883501..1884511 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7623_RS09770 (Q7623_09735)	-	1884936..1885535 (-)	600	WP_000866703.1	response regulator transcription factor	-
Q7623_RS09775 (Q7623_09740)	-	1885536..1886633 (-)	1098	WP_000893503.1	sensor histidine kinase	-
Q7623_RS09780 (Q7623_09745)	-	1886633..1887370 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7623_RS09785 (Q7623_09750)	-	1887372..1888256 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
Q7623_RS09790 (Q7623_09755)	-	1888243..1888437 (-)	195	WP_000715302.1	hypothetical protein	-
Q7623_RS09795 (Q7623_09760)	-	1888434..1888640 (-)	207	Protein_1918	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=864141 Q7623_RS09765 WP_000990607.1 1883501..1884511(-) (ccpA) [Streptococcus pneumoniae strain 2014S11-203]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=864141 Q7623_RS09765 WP_000990607.1 1883501..1884511(-) (ccpA) [Streptococcus pneumoniae strain 2014S11-203]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568