Detailed information NTG0863863

Bioinformatically predicted

Overview

• Name: amiA3
• Type: Regulator
• Locus tag: Q7626_RS01660
• Genome accession: NZ_CP131707
• Coordinates: 320088..322070 (+)
• Length: 660 a.a.
• NCBI ID: WP_000842577.1
• Uniprot ID: A0AA95DAP5
• Organism: Streptococcus pneumoniae strain 2018C08-270
• Function: binding to XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	308230..319288	320088..322070	flank	800
IS/Tn	319377..319766	320088..322070	flank	322

Gene organization within MGE regions

Location: 308230..322070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7626_RS01595 (Q7626_01595)	-	308230..308736 (+)	507	WP_000578432.1	glycosyltransferase	-
Q7626_RS01600 (Q7626_01600)	-	308846..309928 (+)	1083	WP_224332056.1	beta-carotene 15,15'-monooxygenase	-
Q7626_RS01605 (Q7626_01605)	-	309930..310958 (+)	1029	WP_000405438.1	glycosyltransferase family 2 protein	-
Q7626_RS01610 (Q7626_01610)	-	310966..311922 (+)	957	WP_000389755.1	glycosyltransferase family 2 protein	-
Q7626_RS01615 (Q7626_01615)	-	311938..312846 (+)	909	WP_000570495.1	capsular polysaccharide synthesis protein	-
Q7626_RS01620 (Q7626_01620)	-	312851..314314 (+)	1464	WP_000066241.1	flippase	-
Q7626_RS01625 (Q7626_01625)	-	314672..314917 (+)	246	WP_224332055.1	acyltransferase family protein	-
Q7626_RS01630	-	315006..315506 (+)	501	WP_330162723.1	acyltransferase family protein	-
Q7626_RS01635 (Q7626_01630)	-	315508..316656 (+)	1149	WP_000261151.1	CDP-glycerol--glycerophosphate glycerophosphotransferase	-
Q7626_RS01640 (Q7626_01635)	-	316692..317720 (+)	1029	WP_000794264.1	iron-containing alcohol dehydrogenase family protein	-
Q7626_RS01645 (Q7626_01640)	-	317736..318440 (+)	705	WP_000645464.1	phosphocholine cytidylyltransferase family protein	-
Q7626_RS01650 (Q7626_01645)	-	318455..319288 (+)	834	WP_000779206.1	HAD-IIA family hydrolase	-
Q7626_RS01655 (Q7626_01650)	-	319377..319769 (-)	393	Protein_323	transposase	-
Q7626_RS01660 (Q7626_01655)	amiA3	320088..322070 (+)	1983	WP_000842577.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 660 a.a.
• Molecular weight: 73022.64 Da
• Isoelectric Point: 4.7548

>NTDB_id=863863 Q7626_RS01660 WP_000842577.1 320088..322070(+) (amiA3) [Streptococcus pneumoniae strain 2018C08-270]
MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSDEQKASTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVVIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEAT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide

• Length: 1983 bp

>NTDB_id=863863 Q7626_RS01660 WP_000842577.1 320088..322070(+) (amiA3) [Streptococcus pneumoniae strain 2018C08-270]
ATGAAAAGTTCAAAACTATTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGCACTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTCTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGGGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATGAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATCTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATACACATCTAAG
ACCAGCGACGAACAAAAGGCATCGACTAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCCTTTGGTTTTGA
TCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTTACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCCTTACA
AGCAGAAGGTGTGACATTCCCAATTCATTTGGATATGCCAGTTGACCAAACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCGGATAATGTAGTCATTGATATTCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGCGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGGCTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATTTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGTACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

• Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5) (77-519)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiA3	Streptococcus thermophilus LMD-9	58.396	100	0.585
amiA3	Streptococcus thermophilus LMG 18311	58.094	100	0.582
amiA	Streptococcus salivarius strain HSISS4	57.943	100	0.58