Detailed information NTG0863833

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: Q7627_RS09530
• Genome accession: NZ_CP131706
• Coordinates: 1852838..1853848 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 2018N21-288
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1847838..1858848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7627_RS09505 (Q7627_09485)	-	1849003..1849297 (-)	295	Protein_1860	hypothetical protein	-
Q7627_RS09510 (Q7627_09490)	-	1849459..1849911 (+)	453	WP_000079148.1	universal stress protein	-
Q7627_RS09515 (Q7627_09495)	-	1849946..1851334 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
Q7627_RS09520 (Q7627_09500)	-	1851400..1852362 (+)	963	WP_001124786.1	asparaginase	-
Q7627_RS09525 (Q7627_09505)	-	1852391..1852774 (-)	384	WP_001092022.1	hypothetical protein	-
Q7627_RS09530 (Q7627_09510)	ccpA	1852838..1853848 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
Q7627_RS09535 (Q7627_09515)	-	1854273..1854872 (-)	600	WP_000866703.1	response regulator transcription factor	-
Q7627_RS09540 (Q7627_09520)	-	1854873..1855970 (-)	1098	WP_000893503.1	sensor histidine kinase	-
Q7627_RS09545 (Q7627_09525)	-	1855970..1856707 (-)	738	WP_000832916.1	ABC transporter permease	-
Q7627_RS09550 (Q7627_09530)	-	1856709..1857593 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
Q7627_RS09555 (Q7627_09535)	-	1857580..1857774 (-)	195	WP_000715302.1	hypothetical protein	-
Q7627_RS09560 (Q7627_09540)	-	1857771..1857977 (-)	207	Protein_1871	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=863833 Q7627_RS09530 WP_000990607.1 1852838..1853848(-) (ccpA) [Streptococcus pneumoniae strain 2018N21-288]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=863833 Q7627_RS09530 WP_000990607.1 1852838..1853848(-) (ccpA) [Streptococcus pneumoniae strain 2018N21-288]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568