Detailed information NTG0863832

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: Q7627_RS09370
• Genome accession: NZ_CP131706
• Coordinates: 1825022..1826059 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2018N21-288
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1820022..1831059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7627_RS09345 (Q7627_09325)	-	1820761..1822092 (-)	1332	WP_000390042.1	hemolysin family protein	-
Q7627_RS09350 (Q7627_09330)	endA	1822383..1823207 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
Q7627_RS09355 (Q7627_09335)	-	1823246..1823434 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
Q7627_RS09360 (Q7627_09340)	murA	1823427..1824710 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
Q7627_RS09365 (Q7627_09345)	-	1824734..1824964 (-)	231	WP_000250390.1	DUF1146 family protein	-
Q7627_RS09370 (Q7627_09350)	sepM	1825022..1826059 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
Q7627_RS09375 (Q7627_09355)	coaD	1826043..1826531 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
Q7627_RS09380 (Q7627_09360)	rsmD	1826521..1827060 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
Q7627_RS09385 (Q7627_09365)	asnA	1827125..1828117 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
Q7627_RS09390 (Q7627_09370)	-	1828229..1828912 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
Q7627_RS09395 (Q7627_09375)	-	1828968..1829708 (-)	741	WP_000152679.1	RNA methyltransferase	-
Q7627_RS09400 (Q7627_09380)	-	1829742..1830020 (+)	279	WP_001174614.1	acylphosphatase	-
Q7627_RS09405 (Q7627_09385)	yidC	1830098..1831024 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=863832 Q7627_RS09370 WP_001813016.1 1825022..1826059(-) (sepM) [Streptococcus pneumoniae strain 2018N21-288]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=863832 Q7627_RS09370 WP_001813016.1 1825022..1826059(-) (sepM) [Streptococcus pneumoniae strain 2018N21-288]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588