Detailed information NTG0863540

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q7637_RS10415
• Genome accession: NZ_CP131665
• Coordinates: 2089773..2090816 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 2010S01-051
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2084773..2095816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7637_RS10385 (Q7637_10375)	-	2085194..2086450 (-)	1257	WP_001795108.1	aminopeptidase	-
Q7637_RS10390 (Q7637_10380)	-	2086453..2086653 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q7637_RS10395 (Q7637_10385)	-	2086800..2087264 (+)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
Q7637_RS10400 (Q7637_10390)	-	2087271..2087546 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q7637_RS10405 (Q7637_10395)	-	2087824..2089041 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q7637_RS10410 (Q7637_10400)	vraR	2089154..2089783 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q7637_RS10415 (Q7637_10405)	vraS	2089773..2090816 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q7637_RS10420 (Q7637_10410)	liaF	2090813..2091514 (-)	702	WP_126787905.1	cell wall-active antibiotics response protein LiaF	-
Q7637_RS10425 (Q7637_10415)	-	2091529..2091915 (-)	387	WP_001110179.1	hypothetical protein	-
Q7637_RS10430 (Q7637_10420)	map	2092132..2092890 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q7637_RS10435 (Q7637_10425)	-	2093421..2094407 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
Q7637_RS10440 (Q7637_10430)	-	2094838..2095251 (-)	414	WP_001557448.1	hypothetical protein	-
Q7637_RS10445 (Q7637_10435)	-	2095280..2095390 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=863540 Q7637_RS10415 WP_001017131.1 2089773..2090816(-) (vraS) [Staphylococcus aureus strain 2010S01-051]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=863540 Q7637_RS10415 WP_001017131.1 2089773..2090816(-) (vraS) [Staphylococcus aureus strain 2010S01-051]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1