Detailed information NTG0859979

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V76_RS10030
• Genome accession: NZ_CP130541
• Coordinates: 2017110..2018153 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA09-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2012110..2023153

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V76_RS10000	-	2012531..2013787 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V76_RS10005	-	2013790..2013990 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V76_RS10010	-	2014137..2014601 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V76_RS10015	-	2014608..2014883 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V76_RS10020	-	2015161..2016378 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V76_RS10025	vraR	2016491..2017120 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V76_RS10030	vraS	2017110..2018153 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V76_RS10035	liaF	2018150..2018851 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V76_RS10040	-	2018866..2019252 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V76_RS10045	map	2019469..2020227 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V76_RS10050	-	2020756..2021742 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V76_RS10055	-	2022175..2022588 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V76_RS10060	-	2022617..2022727 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859979 Q3V76_RS10030 WP_001017131.1 2017110..2018153(-) (vraS) [Staphylococcus aureus strain SA09-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859979 Q3V76_RS10030 WP_001017131.1 2017110..2018153(-) (vraS) [Staphylococcus aureus strain SA09-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1