Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QUE57_RS19170 Genome accession   NZ_AP027436
Coordinates   3635729..3636361 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain EC571 isolate EC571     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3630729..3641361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE57_RS19145 (MUTS10_36640) yhfG 3630862..3631029 (+) 168 WP_000736851.1 YhfG family protein -
  QUE57_RS19150 (MUTS10_36650) fic 3631019..3631621 (+) 603 WP_001280634.1 putative adenosine monophosphate-protein transferase Fic -
  QUE57_RS19155 (MUTS10_36660) pabA 3631653..3632216 (+) 564 WP_063085668.1 aminodeoxychorismate synthase component 2 -
  QUE57_RS19160 (MUTS10_36670) argD 3632302..3633525 (+) 1224 WP_001551741.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QUE57_RS19165 (MUTS10_36680) yhfK 3633588..3635678 (-) 2091 WP_047656564.1 YccS/YhfK family putative transporter -
  QUE57_RS19170 (MUTS10_36690) crp 3635729..3636361 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QUE57_RS19175 (MUTS10_36700) yhfA 3636663..3637067 (+) 405 WP_096169098.1 OsmC family protein -
  QUE57_RS19180 (MUTS10_36710) prkB 3637122..3637991 (-) 870 WP_001274680.1 phosphoribulokinase -
  QUE57_RS19185 (MUTS10_36720) yheU 3638045..3638263 (-) 219 WP_000907085.1 YheU family protein -
  QUE57_RS19190 (MUTS10_36730) yheT 3638257..3639279 (-) 1023 WP_001551740.1 hydrolase -
  QUE57_RS19195 (MUTS10_36740) yheS 3639279..3641198 (-) 1920 WP_001551739.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=85916 QUE57_RS19170 WP_000242755.1 3635729..3636361(-) (crp) [Escherichia coli strain EC571 isolate EC571]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=85916 QUE57_RS19170 WP_000242755.1 3635729..3636361(-) (crp) [Escherichia coli strain EC571 isolate EC571]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment