Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QUE58_RS22530 Genome accession   NZ_AP027423
Coordinates   4089563..4090195 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain EC261 isolate EC261     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4084563..4095195
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE58_RS22505 (MUTS7_43170) yheS 4084732..4086645 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  QUE58_RS22510 (MUTS7_43180) yheT 4086645..4087667 (+) 1023 WP_000057379.1 hydrolase -
  QUE58_RS22515 (MUTS7_43190) yheU 4087661..4087879 (+) 219 WP_000907085.1 YheU family protein -
  QUE58_RS22520 (MUTS7_43200) prkB 4087933..4088802 (+) 870 WP_001274680.1 phosphoribulokinase -
  QUE58_RS22525 (MUTS7_43210) yhfA 4088857..4089261 (-) 405 WP_001148908.1 OsmC family protein -
  QUE58_RS22530 (MUTS7_43220) crp 4089563..4090195 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QUE58_RS22535 (MUTS7_43230) yhfK 4090246..4092336 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  QUE58_RS22540 (MUTS7_43240) argD 4092403..4093623 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QUE58_RS22545 (MUTS7_43250) pabA 4093709..4094272 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  QUE58_RS22550 (MUTS7_43260) fic 4094304..4094906 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  QUE58_RS22555 (MUTS7_43270) yhfG 4094896..4095063 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=85681 QUE58_RS22530 WP_000242755.1 4089563..4090195(+) (crp) [Escherichia coli strain EC261 isolate EC261]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=85681 QUE58_RS22530 WP_000242755.1 4089563..4090195(+) (crp) [Escherichia coli strain EC261 isolate EC261]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment