Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   V9Z47_RS18465 Genome accession   NZ_CP146670
Coordinates   3629909..3631930 (-) Length   673 a.a.
NCBI ID   WP_000042532.1    Uniprot ID   B7NNK9
Organism   Escherichia coli strain MS 21-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3624909..3636930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9Z47_RS18430 (V9Z47_18430) ybhL 3625022..3625726 (-) 705 WP_001361291.1 Bax inhibitor-1/YccA family protein -
  V9Z47_RS18435 (V9Z47_18435) moaE 3625863..3626315 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  V9Z47_RS18440 (V9Z47_18440) moaD 3626317..3626562 (-) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  V9Z47_RS18445 (V9Z47_18445) moaC 3626555..3627040 (-) 486 WP_000080883.1 cyclic pyranopterin monophosphate synthase MoaC -
  V9Z47_RS18450 (V9Z47_18450) moaB 3627043..3627555 (-) 513 WP_000084642.1 molybdenum cofactor biosynthesis protein B -
  V9Z47_RS18455 (V9Z47_18455) moaA 3627577..3628566 (-) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  V9Z47_RS18460 (V9Z47_18460) yvcK 3628963..3629871 (+) 909 WP_001301716.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  V9Z47_RS18465 (V9Z47_18465) uvrB 3629909..3631930 (-) 2022 WP_000042532.1 excinuclease ABC subunit UvrB Machinery gene
  V9Z47_RS18470 (V9Z47_18470) bioD 3632509..3633186 (-) 678 WP_000044851.1 dethiobiotin synthase -
  V9Z47_RS18475 (V9Z47_18475) bioC 3633179..3633934 (-) 756 WP_000214372.1 malonyl-ACP O-methyltransferase BioC -
  V9Z47_RS18480 (V9Z47_18480) bioF 3633921..3635075 (-) 1155 WP_000118820.1 8-amino-7-oxononanoate synthase -
  V9Z47_RS18485 (V9Z47_18485) bioB 3635072..3636112 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76212.03 Da        Isoelectric Point: 4.8825

>NTDB_id=856725 V9Z47_RS18465 WP_000042532.1 3629909..3631930(-) (uvrB) [Escherichia coli strain MS 21-1]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRDLFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=856725 V9Z47_RS18465 WP_000042532.1 3629909..3631930(-) (uvrB) [Escherichia coli strain MS 21-1]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGTTGTATGGCGAAATGAAAGAATTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAGCAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCATCGGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGCGGTACTTTCCGCGTTCGTGGTGAGGTGATAGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAGAACAACAAGTTGCTTGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCCGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTCGTCGACGAATCTCACGTCACCATTCCACAAAT
TGGTGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTATGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTTGACCCGATTATTGAAGTGCGTCC
GGTAGCGACACAGGTGGATGATCTTCTATCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTGTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAAATCCATGAGCTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
TTTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

Ultra-violet resistance protein B (UvrB)

(552-593)

UvrB/uvrC motif (UVR)

(634-667)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7NNK9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557