Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   V9Z47_RS15725 Genome accession   NZ_CP146670
Coordinates   3108060..3109892 (-) Length   610 a.a.
NCBI ID   WP_001283418.1    Uniprot ID   Q1RAM7
Organism   Escherichia coli strain MS 21-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3103060..3114892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9Z47_RS15675 (V9Z47_15675) azuC 3103068..3103154 (-) 87 WP_010723106.1 stress response protein AzuC -
  V9Z47_RS15680 (V9Z47_15680) yecR 3103418..3103741 (+) 324 WP_001237882.1 YecR-like lipofamily protein -
  V9Z47_RS15685 (V9Z47_15685) ftnA 3103913..3104410 (+) 498 WP_000917208.1 non-heme ferritin -
  V9Z47_RS15690 (V9Z47_15690) yecH 3104448..3104687 (-) 240 WP_000377224.1 YecH family metal-binding protein -
  V9Z47_RS15695 (V9Z47_15695) tyrP 3104878..3106089 (+) 1212 WP_000797555.1 tyrosine transporter TyrP -
  V9Z47_RS15700 (V9Z47_15700) yecA 3106140..3106805 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  V9Z47_RS15720 (V9Z47_15720) pgsA 3107455..3108003 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  V9Z47_RS15725 (V9Z47_15725) uvrC 3108060..3109892 (-) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  V9Z47_RS15730 (V9Z47_15730) letA 3109889..3110545 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  V9Z47_RS15735 (V9Z47_15735) yecU 3110841..3111017 (+) 177 WP_001307856.1 protein YecU -
  V9Z47_RS15740 (V9Z47_15740) yecF 3111004..3111228 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  V9Z47_RS15745 (V9Z47_15745) sdiA 3111296..3112018 (-) 723 WP_001154254.1 transcriptional regulator SdiA -
  V9Z47_RS15750 (V9Z47_15750) tcyN 3112248..3113000 (-) 753 WP_001273012.1 L-cystine ABC transporter ATP-binding protein TcyN -
  V9Z47_RS15755 (V9Z47_15755) tcyL 3112997..3113665 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  V9Z47_RS15760 (V9Z47_15760) dcyD 3113680..3114666 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68202.06 Da        Isoelectric Point: 9.3685

>NTDB_id=856718 V9Z47_RS15725 WP_001283418.1 3108060..3109892(-) (uvrC) [Escherichia coli strain MS 21-1]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGIGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=856718 V9Z47_RS15725 WP_001283418.1 3108060..3109892(-) (uvrC) [Escherichia coli strain MS 21-1]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTACTG
GAACACAACTACATCAAACTTTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGAGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAACAGTGTTTATCGC
AACCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCGCGGATTCGCGACCAAATTCAGGCGGTGCGACGTGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGAGTGGCGTTCGATGCGGGTATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGTGGCGATAGAGCGCGTTATCTGAAACTCGCGCGTACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACACCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCATCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGTGGTTTGCAAGGTTTACGTAACGCCAGCGT
TGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

Helix-hairpin-helix domain (HHH_5)

(558-609)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1RAM7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374