Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QUE76_RS03445 Genome accession   NZ_AP027419
Coordinates   440791..441423 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain EC476 isolate EC476     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 435791..446423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE76_RS03420 (MUTS6_06760) yhfG 435912..436079 (+) 168 WP_000736858.1 YhfG family protein -
  QUE76_RS03425 (MUTS6_06770) fic 436069..436671 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  QUE76_RS03430 (MUTS6_06780) pabA 436703..437266 (+) 564 WP_000601837.1 aminodeoxychorismate synthase component 2 -
  QUE76_RS03435 (MUTS6_06790) argD 437352..438572 (+) 1221 WP_032172363.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QUE76_RS03440 (MUTS6_06800) yhfK 438650..440740 (-) 2091 WP_001571992.1 YccS/YhfK family putative transporter -
  QUE76_RS03445 (MUTS6_06810) crp 440791..441423 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QUE76_RS03450 (MUTS6_06820) yhfA 441725..442129 (+) 405 WP_001148908.1 OsmC family protein -
  QUE76_RS03455 (MUTS6_06830) prkB 442184..443053 (-) 870 WP_001274680.1 phosphoribulokinase -
  QUE76_RS03460 (MUTS6_06840) yheU 443107..443325 (-) 219 WP_000907085.1 YheU family protein -
  QUE76_RS03465 (MUTS6_06850) yheT 443319..444341 (-) 1023 WP_022646191.1 hydrolase -
  QUE76_RS03470 (MUTS6_06860) yheS 444341..446254 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=85549 QUE76_RS03445 WP_000242755.1 440791..441423(-) (crp) [Escherichia coli strain EC476 isolate EC476]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=85549 QUE76_RS03445 WP_000242755.1 440791..441423(-) (crp) [Escherichia coli strain EC476 isolate EC476]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAAGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment