Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   J3989_RS10265 Genome accession   NZ_AP024489
Coordinates   2078276..2080585 (+) Length   769 a.a.
NCBI ID   WP_002225652.1    Uniprot ID   Q70M91
Organism   Neisseria meningitidis strain NIID777     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2073276..2085585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3989_RS10245 (NMNIID777_19240) - 2075329..2076444 (+) 1116 WP_002214517.1 type IV pilus biogenesis protein PilM -
  J3989_RS10250 (NMNIID777_19250) pilN 2076447..2077046 (+) 600 WP_002214520.1 PilN domain-containing protein Machinery gene
  J3989_RS10255 (NMNIID777_19260) - 2077047..2077694 (+) 648 WP_002217908.1 type 4a pilus biogenesis protein PilO -
  J3989_RS10260 (NMNIID777_19270) pilP 2077712..2078257 (+) 546 WP_002214522.1 pilus assembly protein PilP Machinery gene
  J3989_RS10265 (NMNIID777_19280) pilQ 2078276..2080585 (+) 2310 WP_002225652.1 type IV pilus secretin PilQ Machinery gene
  J3989_RS10270 (NMNIID777_19290) - 2081762..2082274 (+) 513 WP_002219790.1 shikimate kinase -
  J3989_RS10275 (NMNIID777_19300) aroB 2082354..2083433 (+) 1080 WP_115155207.1 3-dehydroquinate synthase -
  J3989_RS10280 (NMNIID777_19310) - 2084600..2085442 (+) 843 WP_002230832.1 class II glutamine amidotransferase -

Sequence

Protein


Download         Length: 769 a.a.        Molecular weight: 82473.09 Da        Isoelectric Point: 10.0982

>NTDB_id=85371 J3989_RS10265 WP_002225652.1 2078276..2080585(+) (pilQ) [Neisseria meningitidis strain NIID777]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQQAAAPAKQQAAAPAKQTNIDFRKDGKNAGII
ELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYF
TFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQ
ARNLDMRQQGNIVNIAPRDELLAKDKALLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLISGRGS
VLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGF
GGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIAN
GGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNG
NTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2310 bp        

>NTDB_id=85371 J3989_RS10265 WP_002225652.1 2078276..2080585(+) (pilQ) [Neisseria meningitidis strain NIID777]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAACAGGCGGCAGCAC
CAGCAAAACAACAGGCGGCAGCACCAGCAAAACAAACCAATATCGATTTCCGCAAAGACGGCAAAAATGCCGGCATTATC
GAATTGGCTGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAGCACGACCACATCATCGTTACGCTGAAAAACCA
TACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGCAGACTTTAAAACACCGGTTCAAAAGGTTACGCTGAAACGCC
TCAATAACGACACCCAGCTGATTATCACAACAGCCGGCAACTGGGAACTCGTCAACAAATCCGCCGCGCCCGGATACTTT
ACCTTCCAAGTCCTGCCGAAAAAACAAAACCTCGAGTCAGGCGGCGTGAACAATGCGCCCAAAACCTTCACAGGCCGGAA
AATCTCCCTTGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGATTTTGGCAAAAGAATCCGGAATGAACATTGTTG
CCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAGGATGTGCCTTGGGATCAGGCTTTGGATTTGGTTATGCAG
GCGCGCAACCTCGATATGCGCCAGCAAGGGAATATCGTCAACATCGCGCCCCGCGACGAGCTGCTTGCCAAAGACAAAGC
CCTCTTACAGGCAGAAAAAGACATTGCCGATTTGGGTGCGCTGTATTCCCAAAACTTCCAGTTGAAATACAAAAATGTGG
AAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACACGACCGGAAACCGCAACACGCTTATCAGCGGCAGGGGCAGC
GTGCTGATCGATCCCGCCACCAACACCCTGATTGTTACCGACACCCGCAGCGTCATCGAAAAATTCCGCAAACTGATTGA
CGAATTGGACGTACCCGCGCAACAAGTGATGATTGAGGCGCGTATCGTCGAAGCGGCAGACGGCTTCTCGCGCGATTTGG
GCGTTAAATTCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAAGCGCATTCGGCTGGGGGGTAAACTCCGGCTTC
GGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATTACCGCTGCCGCAAACAGCATTTCGCTGGTGCG
CGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATCGCTTTCAAAAACCAAAACGCTTGCCAATCCGC
GCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCTGGTTACGAAATTCCTTTCACCGTAACCTCAATCGCGAAC
GGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTCTTGGGGCTGACCGTTACGCCGAACATCACGCCCGACGGCCA
AATCATTATGACCGTCAAAATCAACAAGGACTCGCCTGCGCAATGTGCCTCCGGTAATCAGACGATCCTGTGTATTTCGA
CCAAAAACCTGAATACGCAGGCTATGGTTGAAAACGGCGGCACATTGATTGTCGGCGGTATTTATGAAGAAGACAACGGC
AATACGCTGACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGCAACCTCTTTAAAACACGCGGGAAAAAAACCGA
CCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGCCGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(444-515)

Bacterial type II and III secretion system protein (Secretin)

(601-760)

Secretin and TonB N terminus short domain (STN)

(371-416)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 4AQZ
  PDB 4AV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

100

100

1
  pilQ Neisseria meningitidis M1080

98.309

100

0.983
  pilQ Neisseria gonorrhoeae strain FA1090

91.157

100

0.912

Multiple sequence alignment