Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QUE29_RS18650 Genome accession   NZ_AP027258
Coordinates   3758135..3758767 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain JNE151685     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3753135..3763767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE29_RS18625 (JNE151685_35490) yheS 3753304..3755217 (+) 1914 WP_182533473.1 ABC transporter ATP-binding protein -
  QUE29_RS18630 (JNE151685_35500) yheT 3755217..3756239 (+) 1023 WP_000057379.1 hydrolase -
  QUE29_RS18635 (JNE151685_35510) yheU 3756233..3756451 (+) 219 WP_000907085.1 YheU family protein -
  QUE29_RS18640 (JNE151685_35520) prkB 3756505..3757374 (+) 870 WP_001274680.1 phosphoribulokinase -
  QUE29_RS18645 (JNE151685_35530) yhfA 3757429..3757833 (-) 405 WP_001148908.1 OsmC family protein -
  QUE29_RS18650 (JNE151685_35540) crp 3758135..3758767 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QUE29_RS18655 (JNE151685_35550) yhfK 3758818..3760908 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  QUE29_RS18660 (JNE151685_35560) argD 3760975..3762195 (-) 1221 WP_182533474.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QUE29_RS18665 (JNE151685_35570) pabA 3762281..3762844 (-) 564 WP_182533475.1 aminodeoxychorismate synthase component 2 -
  QUE29_RS18670 (JNE151685_35580) fic 3762876..3763478 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  QUE29_RS18675 (JNE151685_35590) yhfG 3763468..3763635 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=85345 QUE29_RS18650 WP_000242755.1 3758135..3758767(+) (crp) [Escherichia coli strain JNE151685]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=85345 QUE29_RS18650 WP_000242755.1 3758135..3758767(+) (crp) [Escherichia coli strain JNE151685]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment