Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6U64_RS09835 Genome accession   NZ_CP145862
Coordinates   2116594..2118537 (-) Length   647 a.a.
NCBI ID   WP_022495805.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS4     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2111594..2123537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS09810 (V6U64_09815) cinA 2112147..2113415 (-) 1269 WP_080611071.1 competence/damage-inducible protein A Machinery gene
  V6U64_RS09815 (V6U64_09820) - 2113512..2114066 (-) 555 WP_080611069.1 DNA-3-methyladenine glycosylase I -
  V6U64_RS09820 (V6U64_09825) ruvA 2114075..2114665 (-) 591 WP_004181981.1 Holliday junction branch migration protein RuvA Machinery gene
  V6U64_RS09825 (V6U64_09830) - 2114946..2116195 (+) 1250 Protein_1895 ISL3 family transposase -
  V6U64_RS09830 (V6U64_09835) - 2116242..2116463 (-) 222 WP_080611067.1 hypothetical protein -
  V6U64_RS09835 (V6U64_09840) hexB 2116594..2118537 (-) 1944 WP_022495805.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6U64_RS09840 (V6U64_09845) - 2118589..2118894 (-) 306 WP_042762228.1 hypothetical protein -
  V6U64_RS09845 (V6U64_09850) - 2119073..2119510 (+) 438 WP_059749062.1 LytTR family DNA-binding domain-containing protein -
  V6U64_RS09850 (V6U64_09855) - 2119507..2119962 (+) 456 WP_021143431.1 DUF3021 domain-containing protein -
  V6U64_RS09855 (V6U64_09860) hexA 2119996..2122554 (-) 2559 WP_410536632.1 DNA mismatch repair protein MutS Machinery gene
  V6U64_RS09860 (V6U64_09865) - 2122547..2122906 (-) 360 WP_410536634.1 YlbF family regulator -
  V6U64_RS09865 (V6U64_09870) argR 2122906..2123334 (-) 429 WP_171963598.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72501.59 Da        Isoelectric Point: 5.2049

>NTDB_id=853442 V6U64_RS09835 WP_022495805.1 2116594..2118537(-) (hexB) [Streptococcus salivarius strain KSS4]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLISESESPVSLVENKP
QPSVKQAQRSADEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=853442 V6U64_RS09835 WP_022495805.1 2116594..2118537(-) (hexB) [Streptococcus salivarius strain KSS4]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTCAAAGAGTTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGTGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGACCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTAAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGATATGGCTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAGATTGATCCTTACT
TGGCCGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCA
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACTAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTATATCGGAGTCAGAGTCTCCAGTTTCATTGGTAGAAAACAAACCG
CAACCTTCTGTTAAACAGGCACAGCGTTCAGCAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAACTCTGGACAATGAGGAAACATCAACCTTCCCTGAGTTGGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCTCAAGGACAAGGTGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATCGGTGAGGTTGACAGCAGTCTACAACAGCTTTTGGTTCCTTATCTCTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGTCCCTTCTGAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAATA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTCAAGACCTACCGTGCTGAGCTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCACTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGAATTCAAGAAAATCATACCAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.512

100

0.705