Detailed information NTG0853443

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U64_RS09855
• Genome accession: NZ_CP145862
• Coordinates: 2119996..2122554 (-)
• Length: 852 a.a.
• NCBI ID: WP_410536632.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS4
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2114996..2127554

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U64_RS09830 (V6U64_09835)	-	2116242..2116463 (-)	222	WP_080611067.1	hypothetical protein	-
V6U64_RS09835 (V6U64_09840)	hexB	2116594..2118537 (-)	1944	WP_022495805.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U64_RS09840 (V6U64_09845)	-	2118589..2118894 (-)	306	WP_042762228.1	hypothetical protein	-
V6U64_RS09845 (V6U64_09850)	-	2119073..2119510 (+)	438	WP_059749062.1	LytTR family DNA-binding domain-containing protein	-
V6U64_RS09850 (V6U64_09855)	-	2119507..2119962 (+)	456	WP_021143431.1	DUF3021 domain-containing protein	-
V6U64_RS09855 (V6U64_09860)	hexA	2119996..2122554 (-)	2559	WP_410536632.1	DNA mismatch repair protein MutS	Machinery gene
V6U64_RS09860 (V6U64_09865)	-	2122547..2122906 (-)	360	WP_410536634.1	YlbF family regulator	-
V6U64_RS09865 (V6U64_09870)	argR	2122906..2123334 (-)	429	WP_171963598.1	arginine repressor	-
V6U64_RS09870 (V6U64_09875)	argS	2123489..2125180 (+)	1692	WP_045772358.1	arginine--tRNA ligase	-
V6U64_RS09875 (V6U64_09880)	purB	2126059..2127357 (-)	1299	WP_002886310.1	adenylosuccinate lyase	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95539.73 Da
• Isoelectric Point: 4.6601

>NTDB_id=853443 V6U64_RS09855 WP_410536632.1 2119996..2122554(-) (hexA) [Streptococcus salivarius strain KSS4]
MAKEKVSPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLSYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVNGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQ
EKPATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=853443 V6U64_RS09855 WP_410536632.1 2119996..2122554(-) (hexA) [Streptococcus salivarius strain KSS4]
ATGGCTAAGGAAAAAGTATCTCCAGGAATGCAACAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTT
TCGGATGGGGGATTTTTACGAATTATTTTACGATGATGCCGTTAAGGCTGCTCAAATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCAGATAATCCCATTCCTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAAGTAGCCATTGCTGAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGTACAGTGGTTGACAGCTCTAAACCTGATAATGCCAATAATTTCTTGGTAGCCATTGACAAGG
CTGGAAGTCGATTCGGTCTGTCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTGGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTT
GGTGAAGCAACTCAACCTTCTACTTTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ACTTGGAAAGTAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGTTAAGCCATTTACAAAAG
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCGAGTTTGGATTTGCTGGAAAATGCTAG
AACAGGTAAGAAACACGGTTCTCTTTTCTGGCTCCTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGTACTT
GGATTGACCGTCCTTTAGTGAATCAGGCTGCTATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGACCTGACTGAGAGTCTTAAAGGGGTTTACGACATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGAAAGGC
TAACCCTAAAGATTTGATTCAGCTAGGTCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATG
ACGAGGCCTTGTCACGTCTTTTACAAGAGCTAGATGCTCTGCCAGAATTAGAAAGTCTGATTCGGTCGGCTATTGATCCC
GATGCTCCAGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGCGAGGGGACGTCATGGATTGCAGACATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGGTTTGGAACTGCTGAGTTGGCTAAAATTGAAGGTGAAATGCTCGAGGCACGTGAAAAGTC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTTCGTGAGCAGGTGGAACGCTATATTGATCGTTTGCAATCTTTGGCTA
AGGCTATTGCGACAGTCGATGTGCTTCAGAGTTTGGCTGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTTAAT
GATGAACATCGTATCGTTATTGATCAAGGTCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAA
CACGATTACCTTTGACAGTCAGACCAATGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGTC
AGTTGGCCTTGTCAGTCGTTATGGCTCAGATGGGGTCTTACGTACCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCC
ATCTATACACGTATTGGTGCTGCAGATGACTTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGGCGTGGGACAGCCACCTATGACGGTATGG
CTCTGGCCCAGTCTATCATTGAGTTTATTCATGACAAGGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCAATGGCCCAGCCGATAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCCGACACCATCTTGACACAACTAGAGGGCGAGACAGTCACCATCCAACCTCAGGAAAAGGTATCGCCTCAA
GAGAAGCCAGCCACTGAAACACATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTACGTGATTTGGACATTTACAATATGACACCGATGCAGGTCATGATGGCTGTAGCAGATTTGAAACAGAAATTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.857	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	36.069	100	0.366