Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   J3989_RS00700 Genome accession   NZ_AP024489
Coordinates   165404..165868 (-) Length   154 a.a.
NCBI ID   WP_162467419.1    Uniprot ID   -
Organism   Neisseria meningitidis strain NIID777     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 154173..165703 165404..165868 flank -299


Gene organization within MGE regions


Location: 154173..165868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3989_RS00650 (NMNIID777_01230) - 154173..154856 (-) 684 WP_207177133.1 hypothetical protein -
  J3989_RS00655 (NMNIID777_01240) - 154927..155079 (-) 153 WP_003754616.1 hypothetical protein -
  J3989_RS00660 (NMNIID777_01250) lpt3 155542..157119 (+) 1578 WP_180301862.1 lipooligosaccharide phosphoethanolamine transferase -
  J3989_RS00665 (NMNIID777_01260) - 157221..160646 (+) 3426 WP_240003773.1 DUF3418 domain-containing protein -
  J3989_RS00670 - 160669..161091 (-) 423 WP_002214928.1 very short patch repair endonuclease -
  J3989_RS00675 (NMNIID777_01280) - 161095..162741 (-) 1647 WP_101116008.1 TIGR02391 family protein -
  J3989_RS00680 (NMNIID777_01290) - 162755..163810 (-) 1056 WP_002214930.1 DNA cytosine methyltransferase -
  J3989_RS00685 (NMNIID777_01300) - 164100..164252 (+) 153 WP_002223150.1 hypothetical protein -
  J3989_RS10715 (NMNIID777_01310) - 164383..164706 (+) 324 WP_202052896.1 5'-nucleotidase -
  J3989_RS00695 (NMNIID777_01320) comP 164867..165316 (-) 450 WP_002237378.1 type IV pilin protein Machinery gene
  J3989_RS00700 comE 165404..165868 (-) 465 WP_162467419.1 ComEA family DNA-binding protein Machinery gene

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16573.86 Da        Isoelectric Point: 10.8645

>NTDB_id=85327 J3989_RS00700 WP_162467419.1 165404..165868(-) (comE) [Neisseria meningitidis strain NIID777]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=85327 J3989_RS00700 WP_162467419.1 165404..165868(-) (comE) [Neisseria meningitidis strain NIID777]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGTGCGCCCGCACCAAAAGGCCCGGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment