Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   J3989_RS00695 Genome accession   NZ_AP024489
Coordinates   164867..165316 (-) Length   149 a.a.
NCBI ID   WP_002237378.1    Uniprot ID   A0A0U1RHA9
Organism   Neisseria meningitidis strain NIID777     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 154173..165703 164867..165316 within 0


Gene organization within MGE regions


Location: 154173..165703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3989_RS00650 (NMNIID777_01230) - 154173..154856 (-) 684 WP_207177133.1 hypothetical protein -
  J3989_RS00655 (NMNIID777_01240) - 154927..155079 (-) 153 WP_003754616.1 hypothetical protein -
  J3989_RS00660 (NMNIID777_01250) lpt3 155542..157119 (+) 1578 WP_180301862.1 lipooligosaccharide phosphoethanolamine transferase -
  J3989_RS00665 (NMNIID777_01260) - 157221..160646 (+) 3426 WP_240003773.1 DUF3418 domain-containing protein -
  J3989_RS00670 - 160669..161091 (-) 423 WP_002214928.1 very short patch repair endonuclease -
  J3989_RS00675 (NMNIID777_01280) - 161095..162741 (-) 1647 WP_101116008.1 TIGR02391 family protein -
  J3989_RS00680 (NMNIID777_01290) - 162755..163810 (-) 1056 WP_002214930.1 DNA cytosine methyltransferase -
  J3989_RS00685 (NMNIID777_01300) - 164100..164252 (+) 153 WP_002223150.1 hypothetical protein -
  J3989_RS10715 (NMNIID777_01310) - 164383..164706 (+) 324 WP_202052896.1 5'-nucleotidase -
  J3989_RS00695 (NMNIID777_01320) comP 164867..165316 (-) 450 WP_002237378.1 type IV pilin protein Machinery gene

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16864.83 Da        Isoelectric Point: 9.7951

>NTDB_id=85326 J3989_RS00695 WP_002237378.1 164867..165316(-) (comP) [Neisseria meningitidis strain NIID777]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINTVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=85326 J3989_RS00695 WP_002237378.1 164867..165316(-) (comP) [Neisseria meningitidis strain NIID777]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATACAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RHA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

99.329

100

0.993
  comP Neisseria meningitidis 8013

98.658

100

0.987
  comP Neisseria subflava NJ9703

48.98

98.658

0.483

Multiple sequence alignment