Detailed information NTG0853222

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U62_RS09765
• Genome accession: NZ_CP145860
• Coordinates: 2096992..2099550 (-)
• Length: 852 a.a.
• NCBI ID: WP_038675013.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS2
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2091992..2104550

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U62_RS09735 (V6U62_09720)	ruvA	2092492..2093082 (-)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene
V6U62_RS09740 (V6U62_09725)	-	2093240..2093461 (-)	222	WP_022495804.1	hypothetical protein	-
V6U62_RS09745 (V6U62_09730)	hexB	2093592..2095535 (-)	1944	WP_022495805.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U62_RS09750 (V6U62_09735)	-	2095585..2095890 (-)	306	WP_002886319.1	hypothetical protein	-
V6U62_RS09755 (V6U62_09740)	-	2096069..2096506 (+)	438	WP_073686198.1	LytTR family DNA-binding domain-containing protein	-
V6U62_RS09760 (V6U62_09745)	-	2096503..2096958 (+)	456	WP_045768436.1	DUF3021 domain-containing protein	-
V6U62_RS09765 (V6U62_09750)	hexA	2096992..2099550 (-)	2559	WP_038675013.1	DNA mismatch repair protein MutS	Machinery gene
V6U62_RS09770 (V6U62_09755)	-	2099543..2099902 (-)	360	WP_002889586.1	YlbF family regulator	-
V6U62_RS09775 (V6U62_09760)	argR	2099902..2100330 (-)	429	WP_171963651.1	arginine repressor	-
V6U62_RS09780 (V6U62_09765)	argS	2100485..2102176 (+)	1692	WP_195914834.1	arginine--tRNA ligase	-
V6U62_RS09785 (V6U62_09770)	purB	2103050..2104348 (-)	1299	WP_195914835.1	adenylosuccinate lyase	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95577.78 Da
• Isoelectric Point: 4.6632

>NTDB_id=853222 V6U62_RS09765 WP_038675013.1 2096992..2099550(-) (hexA) [Streptococcus salivarius strain KSS2]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSHTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQ
EKPATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=853222 V6U62_RS09765 WP_038675013.1 2096992..2099550(-) (hexA) [Streptococcus salivarius strain KSS2]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTT
CCGTATGGGTGATTTTTACGAATTATTTTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTC
GGAATAAGAACGCCGATAATCCCATTCCTATGGCTGGTGTTCCTTACCATTCAGCTCAATCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGG
CTGGAAGTCGATTCGGCCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAGATTTT
GGTCAAGCAACTCAACCTTCTACTTTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACCAGCTTGACAG
ACTTGGAAAGCAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTCAGTCATTTACAAAAG
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAG
AACGGGCAAGAAACACGGTTCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGCACTT
GGATTGATCGTCCTTTAGTGAATCAGGCTGCAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGACCTGACTGAGAGTCTTAAAGGGGTTTACGATATTGAGCGCTTAGCCAGTCGAGTTTCCTTTGGCAAGGC
TAATCCTAAAGATTTGATTCAACTAGGTCATACCTTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATG
ATGAGGCCTTGTCACGTCTTTTACAAGAATTGGATGCTCTGCCAGAATTAGAAAGTCTGATTCGGTCAGCTATTGATCCC
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGCGAGGGGACGTCATGGATTGCGGATATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGCTATGGAACCGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAGTC
ATCAACGCTCGAATATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTA
AGGCCATTGCGACAGTCGATGTTCTTCAGAGCTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATTGTTATTGATCAAGGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAA
CACGATTACCTTTGACAGTCATACCAATGTTCAGCTCATCACAGGGCCAAATATGAGTGGTAAATCTACCTATATGCGTC
AGTTGGCTTTGTCAGTCGTTATGGCTCAGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCT
ATCTATACACGTATTGGTGCTGCAGATGATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTAGGACGTGGGACAGCCACCTATGACGGTATGG
CTCTGGCCCAGTCTATCATTGAGTTTATTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCCGATAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAACTAGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAA
GAGAAGCCTGCCACTGAAACGCATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTACGTGATTTGGACATTTACAATATGACACCGATGCAAGTCATGATGGCTGTAGCGGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.857	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.723	100	0.363