Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6U62_RS09745 Genome accession   NZ_CP145860
Coordinates   2093592..2095535 (-) Length   647 a.a.
NCBI ID   WP_022495805.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2088592..2100535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS09715 (V6U62_09700) spx 2088823..2089221 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  V6U62_RS09720 (V6U62_09705) recA 2089389..2090528 (-) 1140 WP_002886327.1 recombinase RecA Machinery gene
  V6U62_RS09725 (V6U62_09710) cinA 2090564..2091832 (-) 1269 WP_014633777.1 competence/damage-inducible protein A Machinery gene
  V6U62_RS09730 (V6U62_09715) - 2091929..2092483 (-) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  V6U62_RS09735 (V6U62_09720) ruvA 2092492..2093082 (-) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  V6U62_RS09740 (V6U62_09725) - 2093240..2093461 (-) 222 WP_022495804.1 hypothetical protein -
  V6U62_RS09745 (V6U62_09730) hexB 2093592..2095535 (-) 1944 WP_022495805.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6U62_RS09750 (V6U62_09735) - 2095585..2095890 (-) 306 WP_002886319.1 hypothetical protein -
  V6U62_RS09755 (V6U62_09740) - 2096069..2096506 (+) 438 WP_073686198.1 LytTR family DNA-binding domain-containing protein -
  V6U62_RS09760 (V6U62_09745) - 2096503..2096958 (+) 456 WP_045768436.1 DUF3021 domain-containing protein -
  V6U62_RS09765 (V6U62_09750) hexA 2096992..2099550 (-) 2559 WP_038675013.1 DNA mismatch repair protein MutS Machinery gene
  V6U62_RS09770 (V6U62_09755) - 2099543..2099902 (-) 360 WP_002889586.1 YlbF family regulator -
  V6U62_RS09775 (V6U62_09760) argR 2099902..2100330 (-) 429 WP_171963651.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72501.59 Da        Isoelectric Point: 5.2049

>NTDB_id=853221 V6U62_RS09745 WP_022495805.1 2093592..2095535(-) (hexB) [Streptococcus salivarius strain KSS2]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLISESESPVSLVENKP
QPSVKQAQRSADEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=853221 V6U62_RS09745 WP_022495805.1 2093592..2095535(-) (hexB) [Streptococcus salivarius strain KSS2]
ATGCCAAAAATCATCGAATTACCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTTAAAGAGTTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGATAATGGCGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGACCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCGGTTATTGATATTCAGATTGATCCTTATT
TGGCTGATGTCAATGTTCACCCAACCAAGCAGGAAGTACGTATTTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTATATCGGAGTCAGAGTCTCCAGTTTCATTGGTAGAAAACAAACCG
CAACCTTCTGTTAAACAGGCACAGCGTTCAGCAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAACTCTGGACAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATTGGTGAGGTTGACAGCAGTTTACAGCAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCAGACTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAATA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACGAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.512

100

0.705