Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QYE82_RS04180 Genome accession   NZ_CP129374
Coordinates   889492..890208 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CSMH-411EB     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 884492..895208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYE82_RS04165 - 885773..886726 (+) 954 WP_002457911.1 LacI family DNA-binding transcriptional regulator -
  QYE82_RS04170 - 886986..888458 (+) 1473 WP_002457912.1 sucrose-6-phosphate hydrolase -
  QYE82_RS04175 - 888465..889424 (+) 960 WP_002457913.1 carbohydrate kinase -
  QYE82_RS04180 agrA 889492..890208 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  QYE82_RS04185 agrC 890225..891514 (-) 1290 WP_002457914.1 quorum-sensing sensor histidine kinase AgrC -
  QYE82_RS04190 agrD 891539..891679 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  QYE82_RS04195 - 891685..892248 (-) 564 WP_002457915.1 accessory gene regulator AgrB -
  QYE82_RS04200 hld 892565..892642 (+) 78 WP_002494082.1 delta-hemolysin -
  QYE82_RS04205 - 893022..893807 (-) 786 WP_002457916.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=852915 QYE82_RS04180 WP_002447515.1 889492..890208(-) (agrA) [Staphylococcus epidermidis strain CSMH-411EB]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=852915 QYE82_RS04180 WP_002447515.1 889492..890208(-) (agrA) [Staphylococcus epidermidis strain CSMH-411EB]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
AGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374